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UniProtKB/Swiss-Prot entry P83401


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AL7A1_DICDI
Primary accession number P83401
Secondary accession numbers Q550M6 Q8MYH7
Integrated into Swiss-Prot on November 15, 2002
Sequence was last modified on November 15, 2002 (Sequence version 2)
Annotations were last modified on    September 23, 2008 (Entry version 43)
Name and origin of the protein
Protein name Putative aldehyde dehydrogenase family 7 member A1 homolog
Synonyms EC 1.2.1.3
Antiquitin-1
Gene name
ORFNames: DDB_0231504
From
Dictyostelium discoideum (Slime mold) [TaxID: 44689] 
Taxonomy Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature00847; PubMed=12097910 [NCBI, ExPASy, EBI, Israel, Japan]
Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T., Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R., Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A., Noegel A.A.;
"Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
Nature 418:79-85(2002).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature03481; PubMed=15875012 [NCBI, ExPASy, EBI, Israel, Japan]
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
"The genome of the social amoeba Dictyostelium discoideum.";
Nature 435:43-57(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AC117076; AAM33716.3; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AAFI02000019; EAL68912.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_642906.1; -.
3D structure databases
ModBase P83401.
Organism-specific databases
dictyBase DDB0231504; geneDDB0231504.
Ontologies
GO
GO:0004029; Molecular function: aldehyde dehydrogenase (NAD) activity (inferred from sequence or structural similarity from UniProtKB).
GO:0006081; Biological process: cellular aldehyde metabolic process (inferred from sequence or structural similarity from UniProtKB).
QuickGo view.
Family and domain databases
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; FALSE_NEG.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
BLOCKS P83401.
Genome annotation databases
GeneID 3394123; -.
KEGG ddi:DDB_0231504; -.
Other
ProtoNet P83401.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   509  509     Putative aldehyde dehydrogenase family 7 member A1 homolog. PRO_0000056500
NP_BIND   244   249  6     NAD (By similarity). 
ACT_SITE   266   266        Proton acceptor (By similarity). 
ACT_SITE   300   300        Nucleophile (By similarity). 
SITE   164   164  1     Transition state stabilizer (By similarity). 
Sequence information
Length: 509 AA [This is the length of the unprocessed precursor] Molecular weight: 55190 Da [This is the MW of the unprocessed precursor] CRC64: DD104624407CFC41 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTTFNEYPFL AELGIKAENN DGVFNGKWGG AGEIIKCLNP TNNKVIATVR GAAPEEYETC 

        70         80         90        100        110        120 
IQAMLAAKVK WALTPAPRRG EIVRLIGQAM REKIEPLSKL ISLEMGKIYI EAKGEVQEFI 

       130        140        150        160        170        180 
DVCDYATGLS RSINGQVMPS ERPNHILMET WNPLGLVGII TAFNFPCAVL GWNAAISMIC 

       190        200        210        220        230        240 
GNVQLWKGAS TTSLITLAVS KIIEKVLVEN DVDPAVCCVL IGPGRTVGEQ MIQDKRFGLI 

       250        260        270        280        290        300 
SFTGSTEVGR RISSTVHGYF GKTILELGGN NAIVVAEDAD IELVLRAVLF ASVGTTGQRC 

       310        320        330        340        350        360 
TTCRRLFVHE SLYDTILERL TKAYKTIKIG NPLEEGVLVG PLHTQSAVKE FTEGLEEIKK 

       370        380        390        400        410        420 
QGGKVVIGGN KLDISGGNFV EPTVVAIEHD APIVKTELFV PILYIMKFKN LDDAFAWNNE 

       430        440        450        460        470        480 
VPQGLSSSLF TNNQKNIFKW LGPTGSDCGI VNVNVATNGA EIGGAFGGEK ETGGGRESGS 

       490        500 
DSWKQYCRRS TNTINYGNTM PLSQGINFN 

P83401 in FASTA format

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