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UniProtKB/Swiss-Prot entry P94598

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DHE3_BACTN
Primary accession number P94598
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on November 1, 1997 (Sequence version 2)
Annotations were last modified on    September 2, 2008 (Entry version 56)
Name and origin of the protein
Protein name Glutamate dehydrogenase
Synonyms GDH
EC 1.4.1.3
NAD(P)H-utilizing glutamate dehydrogenase
Gene name
Name: gdhA
OrderedLocusNames: BT_1970
From
Bacteroides thetaiotaomicron [TaxID: 818] [HAMAP proteome]
Taxonomy Bacteria; Bacteroidetes; Bacteroidetes (class); Bacteroidales; Bacteroidaceae; Bacteroides.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482;
PubMed=8955404 [NCBI, ExPASy, EBI, Israel, Japan]
Baggio L., Morrison M.;
"The NAD(P)H-utilizing glutamate dehydrogenase of Bacteroides thetaiotaomicron belongs to enzyme family I, and its activity is affected by trans-acting gene(s) positioned downstream of gdhA.";
J. Bacteriol. 178:7212-7220(1996).
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482;
DOI=10.1126/science.1080029; PubMed=12663928 [NCBI, ExPASy, EBI, Israel, Japan]
Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.;
"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
Science 299:2074-2076(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U82241; AAB40143.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE015928; AAO77077.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_810883.1; -.
3D structure databases
HSSP P24295; 1AUP. [HSSP ENTRY / PDB]
ModBase P94598.
Enzyme and pathway databases
BioCyc BTHE226186:BT_1970-MON; -.
Family and domain databases
InterPro IPR006095; Glu/Leu/Phe/Val_DHase.
IPR006096; Glu/Leu/Phe/Val_DHase_C.
IPR006097; Glu/Leu/Phe/Val_DHase_dimer.
IPR014362; Glu_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR11606:SF2; GLFV_DH; 1.
Pfam PF00208; ELFV_dehydrog; 1.
PF02812; ELFV_dehydrog_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000185; Glu_DH; 1.
PRINTS PR00082; GLFDHDRGNASE.
PROSITE PS00074; GLFV_DEHYDROGENASE; 1.
BLOCKS P94598.
Genome annotation databases
GeneID 1076144; -.
GenomeReviews AE015928_GR; BT_1970.
KEGG bth:BT_1970; -.
NMPDR fig|226186.1.peg.1970; -.
Phylogenomic databases
HOGENOM P94598; -.
Genome annotation databases
CMR P94598; BT_1970.
Other
ProtoNet P94598.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   444  444     Glutamate dehydrogenase. PRO_0000182766
ACT_SITE   124   124        By similarity. 
Sequence information
Length: 444 AA [This is the length of the unprocessed precursor] Molecular weight: 49017 Da [This is the MW of the unprocessed precursor] CRC64: 6563EB81F0746095 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNAAKVLDDL KRRFPNEPEY HQAVEEVLST IEEEYNKHPE FDKANLIERL CIPDRVFQFR 

        70         80         90        100        110        120 
VTWMDDKGNI QTNMGYRVQH NNAIGPYKGG IRFHASVNLS ILKFLAFEQT FKNSLTTLPM 

       130        140        150        160        170        180 
GGGKGGSDFS PRGKSNAEVM RFVQAFMLEL WRHIGPETDV PAGDIGVGGR EVGFMFGMYK 

       190        200        210        220        230        240 
KLAHEFTGTF TGKGREFGGS LIRPEATGYG NIYFLMEMLK TKGTDLKGKV CLVSGSGNVA 

       250        260        270        280        290        300 
QYTIEKVIEL GGKVVTCSDS DGYIYDPDGI DREKLDYIME LKNLYRGRIR EYAEKYGCKY 

       310        320        330        340        350        360 
VEGAKPWGEK CDIALPSATQ NELNGDHARQ LVANGCIAVS EGANMPSTPE AVRVFQDAKI 

       370        380        390        400        410        420 
LYAPGKAANA GGVSVSGLEM TQNSIKLSWS AEEVDEKLKS IMKNIHEACV QYGTEADGYV 

       430        440 
NYVKGANVAG FMKVAKAMMA QGIV
P94598 in FASTA format

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