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UniProtKB/Swiss-Prot entry Q00777


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name P5CR3_BACSU
Primary accession number Q00777
Secondary accession numbers None
Integrated into Swiss-Prot on February 1, 1995
Sequence was last modified on July 15, 1999 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 60)
Name and origin of the protein
Protein name Pyrroline-5-carboxylate reductase 3
Synonyms P5C reductase 3
P5CR 3
EC 1.5.1.2
Gene name
Name: proG
Synonyms: ykeA, yzcA
OrderedLocusNames: BSU12910
From
Bacillus subtilis [TaxID: 1423] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=168;
Devine K.M.;
"Sequence of the Bacillus subtilis genome between xlyA and ykoR.";
Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=168;
DOI=10.1038/36786; PubMed=9384377 [NCBI, ExPASy, EBI, Israel, Japan]
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.;
"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.";
Nature 390:249-256(1997).
[3]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 247-272.
STRAIN=168;
PubMed=1766370 [NCBI, ExPASy, EBI, Israel, Japan]
Mathiopoulos C., Mueller J.P., Slack F.J., Murphy C.G., Patankar S., Bukusoglu G., Sonenshein A.L.;
"A Bacillus subtilis dipeptide transport system expressed early during sporulation.";
Mol. Microbiol. 5:1903-1913(1991).
[4]
FUNCTION.
DOI=10.1128/JB.183.14.4389-4392.2001; PubMed=11418582 [NCBI, ExPASy, EBI, Israel, Japan]
Belitsky B.R., Brill J., Bremer E., Sonenshein A.L.;
"Multiple genes for the last step of proline biosynthesis in Bacillus subtilis.";
J. Bacteriol. 183:4389-4392(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AJ002571; CAA05571.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z99110; CAB13148.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X56678; CAA40001.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F69855; F69855.
RefSeq NP_389174.1; -.
3D structure databases
ModBase Q00777.
Enzyme and pathway databases
BioCyc BSUB224308:BSU1293-MON; -.
Organism-specific databases
SubtiList BG10841; proG. [Micado]
Family and domain databases
InterPro IPR004455; NADP_OxRdtase_F420.
IPR000304; P5CR.
Graphical view of domain structure.
PANTHER PTHR11645; P5CR; 1.
Pfam PF03807; F420_oxidored; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000193; Pyrrol-5-carb_rd; 1.
PROSITE PS00521; P5CR; FALSE_NEG.
BLOCKS Q00777.
Genome annotation databases
GeneID 936776; -.
GenomeReviews AL009126_GR; BSU12910.
KEGG bsu:BSU12910; -.
NMPDR fig|224308.1.peg.1293; -.
Phylogenomic databases
HOGENOM Q00777; -.
Other
LinkHub Q00777; -.
Genome annotation databases
CMR Q00777; BSU12910.
Other
ProtoNet Q00777.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Cytoplasm; NADP; Oxidoreductase; Proline biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   272  272     Pyrroline-5-carboxylate reductase 3. PRO_0000187287
Sequence information
Length: 272 AA [This is the length of the unprocessed precursor] Molecular weight: 30203 Da [This is the MW of the unprocessed precursor] CRC64: 3109430A67868638 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MEQIGLIGYG SMADMIARQL LKHEQIKENE LFIETRTKGE RLRALMSDYP NVSADPLENW 

        70         80         90        100        110        120 
ANTCQLILIC VPPLHVIETM RRLYPYVNRN THIVSIAAGV PLRLLEAETE AGISRVIPAI 

       130        140        150        160        170        180 
TSEAEAGISL VVHSEALAAE KKERLNELLS VFSRVREIKE SNLDVASNLT SSAPGFIAAI 

       190        200        210        220        230        240 
FEELALSAVR NSSLSKEEAF DFLIHSLYGT GKMLIEKNMS FEETLERVAT KGGITGEGAE 

       250        260        270 
VIHASVPDVF DEVFERTLRK YELLTEQVGK QT 

Q00777 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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