NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=741;
DOI=10.1006/bbrc.1993.1219; PubMed=8447834 [NCBI, ExPASy, EBI, Israel, Japan]
Lin J.-W., Chao Y.-F., Weng S.-F.;
"Nucleotide sequence of the luxC gene encoding fatty acid reductase of the lux operon from Photobacterium leiognathi.";
Biochem. Biophys. Res. Commun. 191:314-318(1993).

Comments

FUNCTION: LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.
CATALYTIC ACTIVITY: A long-chain aldehyde + CoA + NADP⁺ = a long-chain acyl-CoA + NADPH.
PATHWAY: Lipid metabolism; bioluminescent fatty acid reduction .
SIMILARITY: Belongs to the luxC family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

X65156; CAA46274.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

JC1475; JC1475.

3D structure databases

ModBase

Q03324.

Family and domain databases

InterPro

IPR016162; Ald_DHase_N.
IPR008670; LuxC.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.

Pfam

PF05893; LuxC; 1.
Pfam graphical view of domain structure.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Luminescence; NADP; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 478`	`478`		`Acyl-CoA reductase.`	`PRO_0000220196`

Sequence information

Length: 478 AA [This is the length of the unprocessed precursor]

Molecular weight: 53858 Da [This is the MW of the unprocessed precursor]

CRC64: D730A3BE2462086B [This is a checksum on the sequence]

        10         20         30         40         50         60 
MIKKIPLIIG GEVQDTSEHD VRELTLNNNT VNVPIITDKD AESITSLKIE NKLNINQIVN 

        70         80         90        100        110        120 
FLYTVGQKWK SENYSRRLTY IRDLVKFMGY SPEMAKLEAN WISMILCSKS ALYDIVENDL 

       130        140        150        160        170        180 
SSRHIVDEWL PQGDCYVKAL PKGKSIHLLA GNVPLSGVTS ILRAILTKNE CIIKTSSADP 

       190        200        210        220        230        240 
FTATALASSF IDTDANHPIT RSMSVMYWSH NEDITIPQKI MNCADVVVAW GGNDAIKWAT 

       250        260        270        280        290        300 
KHSPAHVDIL KFGPKKSISI VDNPTDIKAA AIGVAHDICF YDQQACFSTQ DIYYMGDKLD 

       310        320        330        340        350        360 
VFFDELTKQL NIYKVILPKG DQSFDEKGAF SLTERECLFA KYKVQKGEEQ AWLLTQSPAG 

       370        380        390        400        410        420 
TFGNQPLSRS AYIHHVNDIS EITPYIQNDI TQTVSITPWE ASFKYRDTLA SHGAERIIES 

       430        440        450        460        470 
GMNNIFRVGG AHDGMRPLQR LVKYISHERP STYTTKDVAV KIEQTRYLEE DKFLVFVP

Q03324 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools