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UniProtKB/Swiss-Prot entry Q06458

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NIRB_KLEOX
Primary accession number Q06458
Secondary accession numbers None
Integrated into Swiss-Prot on October 1, 1994
Sequence was last modified on October 1, 1994 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 62)
Name and origin of the protein
Protein name Nitrite reductase [NAD(P)H] large subunit
Synonym EC 1.7.1.4
Gene name
Name: nasB
From
Klebsiella oxytoca [TaxID: 571] 
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Klebsiella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=M5a1;
PubMed=8468296 [NCBI, ExPASy, EBI, Israel, Japan]
Lin J.T., Goldman B.S., Stewart V.;
"Structures of genes nasA and nasB, encoding assimilatory nitrate and nitrite reductases in Klebsiella pneumoniae M5al.";
J. Bacteriol. 175:2370-2378(1993).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L06800; AAA25099.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
ModBase Q06458.
Ontologies
GO
GO:0051537; Molecular function: 2 iron, 2 sulfur cluster binding (inferred from electronic annotation from InterPro).
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding (inferred from electronic annotation from UniProtKB-KW).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0050660; Molecular function: FAD binding (inferred from electronic annotation from InterPro).
GO:0020037; Molecular function: heme binding (inferred from electronic annotation from InterPro).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0050661; Molecular function: NADP binding (inferred from electronic annotation from InterPro).
GO:0008942; Molecular function: nitrite reductase [NAD(P)H] activity (inferred from electronic annotation from InterPro).
GO:0042128; Biological process: nitrate assimilation (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR007419; BFD_Fer2_bd.
IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR006066; Nir_Si_BS.
IPR006067; Nir_Sir_4Fe4S.
IPR005117; NiRdtase/SiRdtase_haem-b_fer.
IPR012744; Nitri_red_NirB.
IPR012748; Nitri_red_NirD.
IPR001100; Pyr_nuc-diS_OxRdtase.
IPR001327; Pyr_OxRdtase_NAD_bd.
IPR005806; Rieske_reg.
Graphical view of domain structure.
Gene3D G3DSA:2.102.10.10; Rieske_reg; 1.
Pfam PF04324; Fer2_BFD; 1.
PF01077; NIR_SIR; 1.
PF03460; NIR_SIR_ferr; 1.
PF00070; Pyr_redox; 1.
PF07992; Pyr_redox_2; 1.
Pfam graphical view of domain structure.
PRINTS PR00368; FADPNR.
PR00411; PNDRDTASEI.
PR00397; SIROHAEM.
ProDom PD000139; FAD_pyr_redox; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR02378; nirD_assim_sml; 1.
TIGR02374; nitri_red_nirB; 1.
PROSITE PS00365; NIR_SIR; 1.
PS51300; NIRD; 1.
PROSITE graphical view of domain structure (profiles).
ProtoNet Q06458.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; FAD; Flavoprotein; Heme; Iron; Iron-sulfur; Metal-binding; NADP; Nitrate assimilation; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   957  957     Nitrite reductase [NAD(P)H] large subunit. PRO_0000199963
NP_BIND   44    79  36     FAD (Potential). 
NP_BIND   193   225  33     NAD or NADP (Potential). 
METAL   639   639        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   645   645        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   679   679        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   683   683        Iron (siroheme axial ligand) (By similarity). 
METAL   683   683        Iron-sulfur (4Fe-4S) (By similarity). 
Sequence information
Length: 957 AA [This is the length of the unprocessed precursor] Molecular weight: 104227 Da [This is the MW of the unprocessed precursor] CRC64: A136CC7FA28C6631 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTKPVLVLVG HGMVGHHFLE QCVSRDLHQQ YRIVVFCEER YAAYDRVHLT EYFAGRSAES 

        70         80         90        100        110        120 
LSLVEGDFFT QHGIELRLSE SVASIDREAR VVRDAFGHET HWDKLVLATG SYPFVPPVPG 

       130        140        150        160        170        180 
HNLEGCFVYR TLDDLDQIAA RAATARRGVV IGGGLLGLEA ANALKQLGLE THVVEFAPNL 

       190        200        210        220        230        240 
MAVQLDNGGA AMLREKISEL GVGVHTSKAT TEIVRNEQGL QLNFRDGSSL ATDMLVFSAG 

       250        260        270        280        290        300 
IRPQDALARS GGLSVGERGG ICIDNQCRTS DPDVLAIGEC ALWENKIYGL VAPGYQMAAR 

       310        320        330        340        350        360 
RAATLAGEAG SFSGADMSTK LKLLGVDVAS FGDAQGRTPG CQSYQWTHGP QQVYKKIVVS 

       370        380        390        400        410        420 
ADGKNLLGGV LVGDAGDYAT LLQMMLNGMA LPKHPESLIL PALEGSRPKA LGVAALPDGA 

       430        440        450        460        470        480 
QICSCHNVSK GDICQAVSGG AGDMAAIKSR TKAATGCGGC SALVKQVMEY QLAEQGVEVK 

       490        500        510        520        530        540 
KDICEHFPWS RQEIYHLVRV NHIRTFEQLI ARYGQGHGCE VCKPLVASVL ASCWNEYLLK 

       550        560        570        580        590        600 
PAHLPLQDTN DRYFANIQKD GTYSVVPRMA AGEVTPDGLI AIGQIAKRYQ LYSKVTGGQR 

       610        620        630        640        650        660 
IDLFGARLEQ LPAIWRELAE AGFETGHAYG KSLRTVKSCV GSTWCRYGVQ DSTGLAVTLE 

       670        680        690        700        710        720 
HRYKGLRAPH KIKMAVSGCT RECAEAQGKD IGVIATEKGW NLYVCGNGGM KPRHADLFAS 

       730        740        750        760        770        780 
DLDEATLIRS IDRLLMFYIR TADRLQRTST WMDNLEGGVD YLREMILEDS LGIGEELEQE 

       790        800        810        820        830        840 
MARVVESYQC EWQTTLNDPQ RLALFRSYVN SDEPDETVQR QTLRGQPQLA PFAAQGEPAL 

       850        860        870        880        890        900 
PSRPWQAICD LDAIPQQAGI GARLGERQIA LFRFGDQVYA LDNLEPGSEA NVLSRGLLGD 

       910        920        930        940        950 
AGGEPIVISP LYKQRIRLRD GRQCDGGEQA VRAWPVKVEN GKVWVGNQQL LARAEAS
Q06458 in FASTA format

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View entry in raw text format (no links)
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