ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q0RI14


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name FOLD2_FRAAA
Primary accession number Q0RI14
Secondary accession numbers None
Integrated into Swiss-Prot on October 2, 2007
Sequence was last modified on September 5, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 18)
Name and origin of the protein
Protein name Bifunctional protein folD 2
Synonyms None
Includes Methylenetetrahydrofolate dehydrogenase
     (EC 1.5.1.5)
Methenyltetrahydrofolate cyclohydrolase
     (EC 3.5.4.9)
Gene name
Name: folD2
OrderedLocusNames: FRAAL4216
From
Frankia alni (strain ACN14a) [TaxID: 326424] [HAMAP proteome]
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Frankineae; Frankiaceae; Frankia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1101/gr.5798407; PubMed=17151343 [NCBI, ExPASy, EBI, Israel, Japan]
Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N., Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A., Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P., Goltsman E., Huang Y., Kopp O.R., Labarre L., Lapidus A., Lavire C., Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J., Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F., Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C., Benson D.R.;
"Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.";
Genome Res. 17:7-15(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CT573213; CAJ62858.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_714410.1; -.
3D structure databases
ModBase Q0RI14.
Enzyme and pathway databases
BioCyc FALN326424:FRAAL4216-MON; -.
Ontologies
GO
GO:0004477; Molecular function: methenyltetrahydrofolate cyclohydrolase activity (inferred from electronic annotation from HAMAP).
GO:0004488; Molecular function: methylenetetrahydrofolate dehydrogenase (NADP+) activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01576; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR000672; THF_DHase/CycOHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00763; THF_DHG_CYH; 1.
PF02882; THF_DHG_CYH_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00085; THFDHDRGNASE.
ProDom PD002300; THFDhg/Cyc_hydro; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00766; THF_DHG_CYH_1; FALSE_NEG.
PS00767; THF_DHG_CYH_2; 1.
BLOCKS Q0RI14.
Genome annotation databases
GeneID 4232739; -.
GenomeReviews CT573213_GR; FRAAL4216.
KEGG fal:FRAAL4216; -.
CMR Q0RI14; FRAAL4216.
Other
ProtoNet Q0RI14.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Histidine biosynthesis; Hydrolase; Methionine biosynthesis; Multifunctional enzyme; NADP; One-carbon metabolism; Oxidoreductase; Purine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   288  288     Bifunctional protein folD 2. PRO_0000305819
Sequence information
Length: 288 AA [This is the length of the unprocessed precursor] Molecular weight: 29318 Da [This is the MW of the unprocessed precursor] CRC64: 4432871FBC0BB6ED [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSAVIIDGKA VAARVRADVA RDVAEFRAAT GRQPGLATVL VGDDPASAVY IGGKRRSCVE 

        70         80         90        100        110        120 
AGMADLHQHL PADTPQDEIA ALLDSLAADP AVSGILLQLP VPEGLDGAAL VGRIPPEKDV 

       130        140        150        160        170        180 
DGLTTASVGL LARGLPGLRP CTPSGIIELL DAYDVELSGA PTVVVGRSEL VGRPVAQLLV 

       190        200        210        220        230        240 
GRNATVTICH SRTRDLAAVC RGADVLVVAA GKQAIIGADA VKPGATVIDV GMHRTEQGLR 

       250        260        270        280 
GDVDFDAVRE VAGRLTPVPG GVGPMTIAML LRNTLLAARA AAEVGSLV 

Q0RI14 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ca flag CBR Canada Mirror sites: Australia  Brazil  China  Korea  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!