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UniProtKB/Swiss-Prot entry Q0T1I7

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CYSI_SHIF8
Primary accession number Q0T1I7
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on September 5, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 18)
Name and origin of the protein
Protein name Sulfite reductase [NADPH] hemoprotein beta-component
Synonyms SIR-HP
SIRHP
EC 1.8.1.2
Gene name
Name: cysI
OrderedLocusNames: SFV_2742
From
Shigella flexneri serotype 5b (strain 8401) [TaxID: 373384] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Shigella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1186/1471-2164-7-173; PubMed=16822325 [NCBI, ExPASy, EBI, Israel, Japan]
Nie H., Yang F., Zhang X., Yang J., Chen L., Wang J., Xiong Z., Peng J., Sun L., Dong J., Xue Y., Xu X., Chen S., Yao Z., Shen Y., Jin Q.;
"Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a.";
BMC Genomics 7:173-173(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000266; ABF04828.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_690133.1; -.
3D structure databases
SMR Q0T1I7; 81-570.
ModBase Q0T1I7.
Enzyme and pathway databases
BioCyc SFLE373384:SFV_2742-MON; -.
Ontologies
GO
GO:0004783; Molecular function: sulfite reductase (NADPH) activity (inferred from electronic annotation from HAMAP).
GO:0000103; Biological process: sulfate assimilation (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01540; -; 1.
PBIL [Tree]
InterPro IPR011786; CysI.
IPR006066; Nir_Si_BS.
IPR006067; Nir_Sir_4Fe4S.
IPR005117; NiRdtase/SiRdtase_haem-b_fer.
Graphical view of domain structure.
Pfam PF01077; NIR_SIR; 1.
PF03460; NIR_SIR_ferr; 2.
Pfam graphical view of domain structure.
PRINTS PR00397; SIROHAEM.
TIGRFAMs TIGR02041; CysI; 1.
PROSITE PS00365; NIR_SIR; 1.
BLOCKS Q0T1I7.
Genome annotation databases
GeneID 4210392; -.
GenomeReviews CP000266_GR; SFV_2742.
KEGG sfv:SFV_2742; -.
Phylogenomic databases
HOGENOM Q0T1I7; -.
Genome annotation databases
CMR Q0T1I7; SFV_2742.
Other
ProtoNet Q0T1I7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Amino-acid biosynthesis; Complete proteome; Cysteine biosynthesis; Heme; Iron; Iron-sulfur; Metal-binding; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   570  570     Sulfite reductase [NADPH] hemoprotein beta-component. PRO_1000068777
METAL   434   434        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   440   440        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   479   479        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   483   483        Iron (siroheme axial ligand) (By similarity). 
METAL   483   483        Iron-sulfur (4Fe-4S) (By similarity). 
Sequence information
Length: 570 AA [This is the length of the unprocessed precursor] Molecular weight: 63962 Da [This is the MW of the unprocessed precursor] CRC64: 0D5A1878926E8573 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSEKHPGPLV VEGKLTDAER MKLESNYLRG TIAEDLNDGL TGGFKGDNFL LIRFHGMYQQ 

        70         80         90        100        110        120 
DDRDIRAERA EQKLEPRHAM LLRCRLPGGV ITTKQWQAID KFAGENTIYG SIRLTNRQTF 

       130        140        150        160        170        180 
QFHGILKKNV KPVHQMLHSV GLDALATAND MNRNVLCTSN PYESQLHAEA YEWAKKISEH 

       190        200        210        220        230        240 
LLPRTRAYAE IWLDQEKVAT TDEEPILGQT YLPRKFKTTV VIPPQNDIDL HANDMNFVAI 

       250        260        270        280        290        300 
AENGKLVGFN LLVGGGLSIE HGNKKTYART ASEFGYLPLE HTLAVAEAVV TTQRDWGNRT 

       310        320        330        340        350        360 
DRKNAKTKYT LERVGVETFK AEVERRAGIK FEPSRPYEFT GRGDRIGWVK GIDDNWHLTL 

       370        380        390        400        410        420 
FIENGRILDY PGRPLKTGLL EIAKIHKGDF RITANQNLII AGVPESEKAK IEKIAKESGL 

       430        440        450        460        470        480 
MNAVTPQREN SMACVSFPTC PLAMAEAERF LPSFIDNIDN LMVKHGVSDE HIVMRVTGCP 

       490        500        510        520        530        540 
NGCGRAMLAE VGLVGKAPGR YNLHLGGNRI GTRIPRMYKE NITEPEILAS LDELIGRWAK 

       550        560        570 
EREAGEGFGD FTVRAGIIRP VLDPARDLWD
Q0T1I7 in FASTA format

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