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UniProtKB/Swiss-Prot entry Q0TT95


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AROE_CLOP1
Primary accession number Q0TT95
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on September 5, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 24)
Name and origin of the protein
Protein name Shikimate dehydrogenase
Synonym EC 1.1.1.25
Gene name
Name: aroE
OrderedLocusNames: CPF_0693
From
Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) [TaxID: 195103] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1101/gr.5238106; PubMed=16825665 [NCBI, ExPASy, EBI, Israel, Japan]
Myers G.S.A., Rasko D.A., Cheung J.K., Ravel J., Seshadri R., DeBoy R.T., Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C., Haft D.H., Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A., Khouri H., Dimitrov G.I., Watkins K.L., Mulligan S., Benton J., Radune D., Fisher D.J., Atkins H.S., Hiscox T., Jost B.H., Billington S.J., Songer J.G., McClane B.A., Titball R.W., Rood J.I., Melville S.B., Paulsen I.T.;
"Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens.";
Genome Res. 16:1031-1040(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000246; ABG83549.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_695145.1; -.
3D structure databases
ModBase Q0TT95.
Ontologies
GO
GO:0004764; Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073; Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00222; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00507; aroE; 1.
BLOCKS Q0TT95.
Genome annotation databases
GeneID 4203210; -.
GenomeReviews CP000246_GR; CPF_0693.
KEGG cpf:CPF_0693; -.
TIGR CPF_0693; -.
Phylogenomic databases
HOGENOM Q0TT95; -.
Other
ProtoNet Q0TT95.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   271  271     Shikimate dehydrogenase. PRO_1000021277
NP_BIND   125   129  5     NADP (By similarity). 
Sequence information
Length: 271 AA [This is the length of the unprocessed precursor] Molecular weight: 30503 Da [This is the MW of the unprocessed precursor] CRC64: D6AEF6024B65AEC0 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKLFGLIGEK LGHSLSPEIH NKVFKDNNID GLYNLFSVKK DFENNIVESL KCLGVKGANV 

        70         80         90        100        110        120 
TIPYKEKVMD QLDIISHEAK AIGAVNTILI KDGKSYGYNT DYYGFGKMLE RAKVNIEGNS 

       130        140        150        160        170        180 
FFVLGAGGAA RSILKYLEDS KAKKIVLVSR DREKAFKKFK DFNINFMSYG ELEEINEEFA 

       190        200        210        220        230        240 
LINTTPCGMY PNINSVAVSE KVIKKFKVAV DIVYNPLETK FLKMAKDNGL KTVDGLFMLV 

       250        260        270 
GQGVKAEEIW NGIKVDKSTE EDIYEELKCR F 

Q0TT95 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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