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UniProtKB/Swiss-Prot entry Q1R3J6

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NRFA_ECOUT
Primary accession number Q1R3J6
Secondary accession numbers None
Integrated into Swiss-Prot on December 12, 2006
Sequence was last modified on May 16, 2006 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 24)
Name and origin of the protein
Protein name Cytochrome c-552 [Precursor]
Synonyms EC 1.7.2.2
Ammonia-forming cytochrome c nitrite reductase
Cytochrome c nitrite reductase
Gene name
Name: nrfA
OrderedLocusNames: UTI89_C4660
From
Escherichia coli (strain UTI89 / UPEC) [TaxID: 364106] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0600938103; PubMed=16585510 [NCBI, ExPASy, EBI, Israel, Japan]
Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A., Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S., Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J., Gordon J.I.;
"Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach.";
Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000243; ABE10068.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_543599.1; -.
3D structure databases
SMR Q1R3J6; 38-478.
ModBase Q1R3J6.
Enzyme and pathway databases
BioCyc ECOL364106:UTI89_C4660-MON; -.
Ontologies
GO
GO:0042597; Cellular component: periplasmic space (inferred from electronic annotation from HAMAP).
GO:0042279; Molecular function: nitrite reductase (cytochrome, ammonia-forming) activity (inferred from electronic annotation from HAMAP).
GO:0006807; Biological process: nitrogen compound metabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01182; -; 1.
PBIL [Tree]
InterPro IPR003321; Cyt_c552.
IPR017570; Cytc_552_NO2Rdtase_formate-dep.
IPR011031; Multihaem_cyt.
Graphical view of domain structure.
Pfam PF02335; Cytochrom_C552; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000243; Cyt_c552; 1.
PROSITE PS51008; MULTIHEME_CYTC; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q1R3J6.
Genome annotation databases
GeneID 3989712; -.
GenomeReviews CP000243_GR; UTI89_C4660.
KEGG eci:UTI89_C4660; -.
Phylogenomic databases
HOGENOM Q1R3J6; -.
Genome annotation databases
CMR Q1R3J6; UTI89_C4660.
Other
ProtoNet Q1R3J6.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Calcium; Complete proteome; Electron transport; Heme; Iron; Metal-binding; Oxidoreductase; Periplasm; Signal; Transport.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
SIGNAL   1    26  26     By similarity. 
CHAIN   27   478  452     Cytochrome c-552. PRO_0000268963
METAL   94    94        Iron (heme 3 axial ligand) (By similarity). 
METAL   126   126        Iron (heme 1 axial ligand) (By similarity). 
METAL   164   164        Iron (heme 2 axial ligand) (By similarity). 
METAL   213   213        Iron (heme 3 axial ligand) (By similarity). 
METAL   215   215        Calcium (By similarity). 
METAL   216   216        Calcium; via carbonyl oxygen (By similarity). 
METAL   261   261        Calcium; via carbonyl oxygen (By similarity). 
METAL   263   263        Calcium (By similarity). 
METAL   275   275        Iron (heme 5 axial ligand) (By similarity). 
METAL   286   286        Iron (heme 4 axial ligand) (By similarity). 
METAL   301   301        Iron (heme 2 axial ligand) (By similarity). 
METAL   318   318        Iron (heme 5 axial ligand) (By similarity). 
METAL   393   393        Iron (heme 4 axial ligand) (By similarity). 
BINDING   122   122        Heme 1 (covalent) (By similarity). 
BINDING   125   125        Heme 1 (covalent) (By similarity). 
BINDING   160   160        Heme 2 (covalent) (By similarity). 
BINDING   163   163        Heme 2 (covalent) (By similarity). 
BINDING   209   209        Heme 3 (covalent) (By similarity). 
BINDING   212   212        Heme 3 (covalent) (By similarity). 
BINDING   216   216        Substrate (By similarity). 
BINDING   264   264        Substrate (By similarity). 
BINDING   282   282        Heme 4 (covalent) (By similarity). 
BINDING   285   285        Heme 4 (covalent) (By similarity). 
BINDING   314   314        Heme 5 (covalent) (By similarity). 
BINDING   317   317        Heme 5 (covalent) (By similarity). 
Sequence information
Length: 478 AA [This is the length of the unprocessed precursor] Molecular weight: 53676 Da [This is the MW of the unprocessed precursor] CRC64: ED06CDA0A5849707 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTRIKINARR IFSLLIPFFF FTSVHAEQTA APATPVTVEA KNETFAPQHP DQYLSWKATS 

        70         80         90        100        110        120 
EQSERVDALA EDPRLVILWA GYPFSRDYNK PRGHAFAVTD VRETLRTGAP KNAEDGPLPM 

       130        140        150        160        170        180 
ACWSCKSPDV ARLIQKDGED GYFHGKWARG GPEIVNNLGC ADCHNTASPE FAKGKPELTL 

       190        200        210        220        230        240 
SRPYAARAME AIGKPFEKAG RFDQQSMVCG QCHVEYYFDG KNKAVKFPWD DGMKVENMEQ 

       250        260        270        280        290        300 
YYDKIAFSDW TNSLSKTPML KAQHPEYETW TAGIHGKNNV TCIDCHMPKV QNAEGKLYTD 

       310        320        330        340        350        360 
HKIGNPFDNF AQTCANCHTQ DKAALQKVVA ERKQSINDLK IKVEDQLVHA HFEAKAALDA 

       370        380        390        400        410        420 
GATEAEMKPI QDDIRHAQWR WDLAIASHGI HMHAPEEGLR MLGTAMDKAA DARTKLARLL 

       430        440        450        460        470 
ATKGITHEIQ IPDISTKEKA QQAIGLNMEQ IKAEKQDFIK TVIPQWEEQA RKNGLLSQ
Q1R3J6 in FASTA format

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