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UniProtKB/Swiss-Prot entry Q1RKF8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name UDG_RICBR
Primary accession number Q1RKF8
Secondary accession numbers None
Integrated into Swiss-Prot on March 20, 2007
Sequence was last modified on May 16, 2006 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 20)
Name and origin of the protein
Protein name UDP-glucose 6-dehydrogenase
Synonyms UDP-Glc dehydrogenase
UDP-GlcDH
UDPGDH
EC 1.1.1.22
Gene name
Name: udg
OrderedLocusNames: RBE_0075
From
Rickettsia bellii (strain RML369-C) [TaxID: 336407] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Rickettsiaceae; Rickettsieae; Rickettsia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1371/journal.pgen.0020076; PubMed=16703114 [NCBI, ExPASy, EBI, Israel, Japan]
Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C., Fournier P.-E., Claverie J.-M., Raoult D.;
"Genome sequence of Rickettsia bellii illuminates the role of amoebae in gene exchanges between intracellular pathogens.";
PLoS Genet. 2:733-744(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000087; ABE04156.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_537245.1; -.
3D structure databases
ModBase Q1RKF8.
Enzyme and pathway databases
BioCyc RBEL336407:RBE_0075-MON; -.
Ontologies
GO
GO:0003979; Molecular function: UDP-glucose 6-dehydrogenase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR013328; DHase_multihelical.
IPR016040; NAD(P)-bd.
IPR017476; Nucleotide_sugar_DH.
IPR014027; UDP-Glc/GDP-Man_DHase_C.
IPR014026; UDP-Glc/GDP-Man_DHase_dimer.
IPR014028; UDP-Glc/GDP-Man_DHase_dimer-bd.
IPR001732; UDP-Glc/GDP-Man_DHase_N.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
G3DSA:3.40.50.1870; UDP-Glc/GDP-Man_DH_C; 1.
PANTHER PTHR11374; UDPG_MGDP_DH_Creg; 1.
Pfam PF00984; UDPG_MGDP_dh; 1.
PF03720; UDPG_MGDP_dh_C; 1.
PF03721; UDPG_MGDP_dh_N; 1.
Pfam graphical view of domain structure.
BLOCKS Q1RKF8.
Genome annotation databases
GeneID 3994979; -.
GenomeReviews CP000087_GR; RBE_0075.
KEGG rbe:RBE_0075; -.
Phylogenomic databases
HOGENOM Q1RKF8; -.
Genome annotation databases
CMR Q1RKF8; RBE_0075.
Other
ProtoNet Q1RKF8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   434  434     UDP-glucose 6-dehydrogenase. PRO_0000281044
NP_BIND   2    19  18     NAD (Potential). 
ACT_SITE   260   260        By similarity. 
Sequence information
Length: 434 AA [This is the length of the unprocessed precursor] Molecular weight: 48268 Da [This is the MW of the unprocessed precursor] CRC64: 53410C577FA28771 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MNITFIGSGY VGLVSGVMMS YLGHNVTCLD NDEAKISKLN KRILPIYETK LDKYFTQALE 

        70         80         90        100        110        120 
HERLKFTSFY NEELKNTEAV FITVGTPSKA SGEADLSYVY EAIDKISLHI NKDCLIVIKS 

       130        140        150        160        170        180 
TVPPNSCNNI INYLKEKGFS FNVASNPEFL REGNAVEDFL YPDRIVIGVN NKESEDILRK 

       190        200        210        220        230        240 
IYMPLTDNGA ELVITDLVTA ELIKYGSNSF LATKIAFINE MANLCEKIGA DIKNLSKGIG 

       250        260        270        280        290        300 
LDKRIGTAFL NAGPGFGGSC FPKDILALNS IIKNNYIDSK ILEAVIRSNK ERPSLMVDKI 

       310        320        330        340        350        360 
ATLLDEDLKG KNIAVLGLTY KAGTDDVRAS PAIEIIKNLL DKGTYVKAFD PMGLENSQKT 

       370        380        390        400        410        420 
FQNENLLYLD SAIKVCDSSD AIIITTEWSE FQALDWQKIY SLVKTPIIID LRNILKADEV 

       430 
ESIGFRYYTV GSKI 

Q1RKF8 in FASTA format

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