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UniProtKB/Swiss-Prot entry Q2KYC8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HGD_BORA1
Primary accession number Q2KYC8
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on March 7, 2006 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 19)
Name and origin of the protein
Protein name Homogentisate 1,2-dioxygenase
Synonyms EC 1.13.11.5
Homogentisicase
Homogentisate oxygenase
Homogentisic acid oxidase
Gene name
Name: hmgA
OrderedLocusNames: BAV0528
From
Bordetella avium (strain 197N) [TaxID: 360910] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Alcaligenaceae; Bordetella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.01927-05; PubMed=16885469 [NCBI, ExPASy, EBI, Israel, Japan]
Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D., Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A., Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J., Parkhill J., Temple L.M.;
"Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction.";
J. Bacteriol. 188:6002-6015(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AM167904; CAJ48133.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_785061.1; -.
3D structure databases
ModBase Q2KYC8.
Ontologies
GO
GO:0004411; Molecular function: homogentisate 1,2-dioxygenase activity (inferred from electronic annotation from HAMAP).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from HAMAP).
GO:0006559; Biological process: L-phenylalanine catabolic process (inferred from electronic annotation from HAMAP).
GO:0006572; Biological process: tyrosine catabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00334; -; 1.
PBIL [Tree]
InterPro IPR005708; Homogentis_dOase.
Graphical view of domain structure.
PANTHER PTHR11056; Homogentis_dOase; 1.
Pfam PF04209; HgmA; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01015; hmgA; 1.
BLOCKS Q2KYC8.
Genome annotation databases
GeneID 6266951; -.
GenomeReviews AM167904_GR; BAV0528.
KEGG bav:BAV0528; -.
NMPDR fig|521.1.peg.1029; -.
Phylogenomic databases
HOGENOM Q2KYC8; -.
Genome annotation databases
CMR Q2KYC8; BAV0528.
Other
ProtoNet Q2KYC8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Phenylalanine catabolism; Tyrosine catabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   432  432     Homogentisate 1,2-dioxygenase. PRO_1000019520
METAL   329   329        Iron (By similarity). 
METAL   335   335        Iron (By similarity). 
METAL   365   365        Iron (By similarity). 
Sequence information
Length: 432 AA [This is the length of the unprocessed precursor] Molecular weight: 47808 Da [This is the MW of the unprocessed precursor] CRC64: 2CEC82ACE2DE950E [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MPLNYQSGFG NACATEALPG ALPQGRNSPQ QCPYGLYAEQ LSGTAFTAPR SENRRSWLYR 

        70         80         90        100        110        120 
IRPGVVHRPF EPYAGAPHWL ADFGTGPVTP NQLRWSPLPL PATPTDFIDG VHTWGGNGGP 

       130        140        150        160        170        180 
DEQSGVGIHL YAANQSMKGR FFYNADAEML LVPQLGRLRL ATEMGLLDLE PLEIAVLPRG 

       190        200        210        220        230        240 
VRFRVELLDA EARGYLLENF GTALRPPELG PIGSNGLANA RDFQTPVAWY EDVEGDFELI 

       250        260        270        280        290        300 
AKFTGGFWRA PLTHSPLDVV AWHGTHAPYK YDLRHFNTIG SISYDHPDPS IFTVLTSPSD 

       310        320        330        340        350        360 
TPGTANLDFA IFPPRILAME NTFRPPWFHR NIASEFMGLI QGVYDAKAEG FAPGGASLHN 

       370        380        390        400        410        420 
CMSGHGPDAD TFEKASVADT SKAHYIRDTM AFMFETRRVI RPTRQALASA QLQGDYYQCW 

       430 
QDLKKHFNPE KA
Q2KYC8 in FASTA format

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