NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goodwin L.A., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.;
"Complete sequence of Desulfovibrio desulfuricans G20.";
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: Shikimate + NADP⁺ = 3-dehydroshikimate + NADPH.
PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and PEP: step 4/7 .
PATHWAY: Context: Aromatic amino acids biosynthesis .
SIMILARITY: Belongs to the shikimate dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000112; ABB40357.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_390052.1; -.

3D structure databases

ModBase

Q30VD9.

Enzyme and pathway databases

BioCyc

DDES207559:DDE_3564-MON; -.

Ontologies

GO:0004764;	Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073;	Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00222; -; 1.
PBIL [Tree]

InterPro

IPR016040; NAD(P)-bd.
IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.

Pfam

PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR00507; aroE; 1.

BLOCKS

Q30VD9.

Genome annotation databases

GeneID

3758544; -.

GenomeReviews

CP000112_GR; Dde_3564.

KEGG

dde:Dde_3564; -.

NMPDR

fig|207559.3.peg.2396; -.

Phylogenomic databases

HOGENOM

Q30VD9; -.

Genome annotation databases

CMR

Q30VD9; Dde_3564.

Other

ProtoNet

Q30VD9.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 279`	`279`	`Shikimate dehydrogenase.`	`PRO_1000021280`
`NP_BIND`	`130 134`	`5`	`NADP (By similarity).`

Sequence information

Length: 279 AA [This is the length of the unprocessed precursor]

Molecular weight: 29799 Da [This is the MW of the unprocessed precursor]

CRC64: 4C577295A27B3491 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTIPRIPRQL YGIIGYPLGH SMSPLLHNWG FELLGEQAAY MAFPVAPEKL AEFICCARML 

        70         80         90        100        110        120 
PVSGLSVTIP HKQAVMPLLD AVTPRAQAAG AVNTLFYDDG KLTGDNTDVY GFLHPLDSCG 

       130        140        150        160        170        180 
TAHAAALVLG AGGAANAVLA ALTARGMCNV TVTNRNGDRA RILAERFGVR CVAWEERHAV 

       190        200        210        220        230        240 
DADLVVNTTP LGMAGDRQAQ TPLDPAFFSS RPAGLAYDLI YNPAQTFFLA SAQAAGWRVL 

       250        260        270 
NGLDMFVAQG AEQFRIWRGR ELPFAQARAL IADALASGC

Q30VD9 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools