NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.;
"Complete sequence of Prochlorococcus marinus str. MIT 9312.";
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: Coproporphyrinogen-III + O₂ + 2 H⁺ = protoporphyrinogen-IX + 2 CO₂ + 2 H₂O.
PATHWAY: Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen III (O2 route): step 1/1 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the aerobic coproporphyrinogen III oxidase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000111; ABB50735.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_398171.1; -.

3D structure databases

ModBase

Q318G0.

Enzyme and pathway databases

BioCyc

PMAR74546:PMT9312_1674-MON; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004109;	Molecular function: coproporphyrinogen oxidase activity (inferred from electronic annotation from HAMAP).
GO:0006779;	Biological process: porphyrin biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00333; -; 1.
PBIL [Tree]

InterPro

IPR001260; Coprogen_oxidas.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.1500.10; Coprogen_oxidas; 1.

PANTHER

PTHR10755; Coprogen_oxidas; 1.

Pfam

PF01218; Coprogen_oxidas; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000166; Coproporphyri_ox; 1.

PRINTS

PR00073; COPRGNOXDASE.

PROSITE

PS01021; COPROGEN_OXIDASE; 1.

BLOCKS

Q318G0.

Genome annotation databases

GeneID

3766496; -.

GenomeReviews

CP000111_GR; PMT9312_1674.

KEGG

pmi:PMT9312_1674; -.

Phylogenomic databases

HOGENOM

Q318G0; -.

Genome annotation databases

CMR

Q318G0; PMT9312_1674.

Other

ProtoNet

Q318G0.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Oxidoreductase; Porphyrin biosynthesis.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 342`	`342`		`Coproporphyrinogen III oxidase, aerobic.`	`PRO_1000019479`

Sequence information

Length: 342 AA [This is the length of the unprocessed precursor]

Molecular weight: 39538 Da [This is the MW of the unprocessed precursor]

CRC64: 317D7A7BF8D60B71 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MLKEPPKNSR EKTKNLLLTL QDKICSGLEN IDGKGKFTEE SWLRDEGGGG RSRVLKNGSI 

        70         80         90        100        110        120 
FEQAGVNFSE VQGKELPQSI ISQRPEAKGH EWFATGTSMV LHPKNPFIPT VHLNYRYFEA 

       130        140        150        160        170        180 
GPVWWFGGGA DLTPFYPYLS DVRNFHKEHK KACEKVDKDL HKVFKPWCDE YFFLKHRNES 

       190        200        210        220        230        240 
RGIGGIFYDY QDGSGNIYRG NNQNGEASKV SENIGKSNLN WDNLFSLAEN CGQAFLPSYL 

       250        260        270        280        290        300 
PIIEKRANKT YTSKEREFQL YRRGRYVEFN LVWDRGTIFG LQTNGRTESI LMSLPPLARW 

       310        320        330        340 
EYGYKAKKGS REEFLTSIFT KPQDWLNDKD LENFCMENNI FD

Q318G0 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools