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UniProtKB/Swiss-Prot entry Q39172


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name P1_ARATH
Primary accession number Q39172
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 57)
Name and origin of the protein
Protein name Probable NADP-dependent oxidoreductase P1
Synonym EC 1.3.1.74
Gene name
Name: P1
OrderedLocusNames: At5g16970
ORFNames: F2K13_120
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=cv. Columbia;
DOI=10.1074/jbc.270.44.26224; PubMed=7592828 [NCBI, ExPASy, EBI, Israel, Japan]
Babiychuk E., Kushnir S., Belles-Boix E., van Montagu M., Inze D.;
"Arabidopsis thaliana NADPH oxidoreductase homologs confer tolerance of yeasts toward the thiol-oxidizing drug diamide.";
J. Biol. Chem. 270:26224-26231(1995).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/35048507; PubMed=11130714 [NCBI, ExPASy, EBI, Israel, Japan]
Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K., Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.;
"Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
Nature 408:823-826(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Z49768; CAA89838.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AL391141; CAC01710.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S57611; S57611.
RefSeq NP_197199.1; -.
UniGene At.22432
3D structure databases
PDB
2J3H; X-ray; 2.50 A; A/B=1-345.[ExPASy / RCSB / EBI]
2J3I; X-ray; 2.80 A; A/B=1-345.[ExPASy / RCSB / EBI]
2J3J; X-ray; 2.80 A; A/B=1-345.[ExPASy / RCSB / EBI]
2J3K; X-ray; 2.80 A; A/B=1-345.[ExPASy / RCSB / EBI]
Detailed list of linked structures.
PDBsum 2J3H; -.
2J3I; -.
2J3J; -.
2J3K; -.
ModBase Q39172.
Organism-specific databases
TAIR At5g16970; -.
Gene expression databases
GermOnline AT5G16970; Arabidopsis thaliana.
Family and domain databases
InterPro IPR002085; AlcDHase_SF_Zn.
IPR013149; AlcDHase_Zn-bd.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR11695; ADH_Sf_Zn; 1.
Pfam PF00107; ADH_zinc_N; 1.
Pfam graphical view of domain structure.
BLOCKS Q39172.
Proteomic databases
ProMEX Q39172; -.
Genome annotation databases
GeneID 831560; -.
GenomeReviews BA000015_GR; AT5G16970.
KEGG ath:AT5G16970; -.
Other
ProtoNet Q39172.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
3D-structure; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   345  345     Probable NADP-dependent oxidoreductase P1. PRO_0000218073
STRAND   2    10  9      
STRAND   14    17  4      
HELIX   20    22  3      
STRAND   23    31  9      
STRAND   36    39  4      
STRAND   41    45  5      
STRAND   47    49  3      
HELIX   54    58  5      
STRAND   79    89  11      
STRAND   99   112  14      
TURN   116   118  3      
STRAND   120   122  3      
HELIX   131   133  3      
TURN   134   136  3      
HELIX   138   148  11      
STRAND   158   163  6      
HELIX   167   178  12      
STRAND   182   189  8      
HELIX   190   198  9      
STRAND   203   207  5      
HELIX   215   221  7      
STRAND   226   233  8      
HELIX   235   242  8      
STRAND   245   253  9      
HELIX   257   259  3      
HELIX   273   277  5      
STRAND   280   283  4      
HELIX   286   292  7      
HELIX   293   305  13      
STRAND   313   318  6      
HELIX   319   321  3      
HELIX   323   330  8      
STRAND   335   343  9      
Sequence information
Length: 345 AA [This is the length of the unprocessed precursor] Molecular weight: 38134 Da [This is the MW of the unprocessed precursor] CRC64: 5AFCEBB2948B2680 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTATNKQVIL KDYVSGFPTE SDFDFTTTTV ELRVPEGTNS VLVKNLYLSC DPYMRIRMGK 

        70         80         90        100        110        120 
PDPSTAALAQ AYTPGQPIQG YGVSRIIESG HPDYKKGDLL WGIVAWEEYS VITPMTHAHF 

       130        140        150        160        170        180 
KIQHTDVPLS YYTGLLGMPG MTAYAGFYEV CSPKEGETVY VSAASGAVGQ LVGQLAKMMG 

       190        200        210        220        230        240 
CYVVGSAGSK EKVDLLKTKF GFDDAFNYKE ESDLTAALKR CFPNGIDIYF ENVGGKMLDA 

       250        260        270        280        290        300 
VLVNMNMHGR IAVCGMISQY NLENQEGVHN LSNIIYKRIR IQGFVVSDFY DKYSKFLEFV 

       310        320        330        340 
LPHIREGKIT YVEDVADGLE KAPEALVGLF HGKNVGKQVV VVARE 

Q39172 in FASTA format

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