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UniProtKB/Swiss-Prot entry Q3AEF5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AROE_CARHZ
Primary accession number Q3AEF5
Secondary accession numbers None
Integrated into Swiss-Prot on March 18, 2008
Sequence was last modified on November 22, 2005 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 24)
Name and origin of the protein
Protein name Shikimate dehydrogenase
Synonym EC 1.1.1.25
Gene name
Name: aroE
OrderedLocusNames: CHY_0623
From
Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) [TaxID: 246194] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales; Thermoanaerobacteraceae; Carboxydothermus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1371/journal.pgen.0010065; PubMed=16311624 [NCBI, ExPASy, EBI, Israel, Japan]
Wu M., Ren Q., Durkin A.S., Daugherty S.C., Brinkac L.M., Dodson R.J., Madupu R., Sullivan S.A., Kolonay J.F., Nelson W.C., Tallon L.J., Jones K.M., Ulrich L.E., Gonzalez J.M., Zhulin I.B., Robb F.T., Eisen J.A.;
"Life in hot carbon monoxide: the complete genome sequence of Carboxydothermus hydrogenoformans Z-2901.";
PLoS Genet. 1:563-574(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000141; ABB14147.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_359479.1; -.
3D structure databases
ModBase Q3AEF5.
Enzyme and pathway databases
BioCyc CHYD246194:CHY_0623-MON; -.
Ontologies
GO
GO:0004764; Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073; Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00222; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00507; aroE; 1.
BLOCKS Q3AEF5.
Genome annotation databases
GeneID 3728671; -.
GenomeReviews CP000141_GR; CHY_0623.
KEGG chy:CHY_0623; -.
NMPDR fig|246194.3.peg.366; -.
TIGR CHY_0623; -.
Phylogenomic databases
HOGENOM Q3AEF5; -.
Other
ProtoNet Q3AEF5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   280  280     Shikimate dehydrogenase. PRO_0000325111
NP_BIND   131   135  5     NADP (By similarity). 
Sequence information
Length: 280 AA [This is the length of the unprocessed precursor] Molecular weight: 30495 Da [This is the MW of the unprocessed precursor] CRC64: FFDAEE2500966396 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MRINGETKLT GIIGYPLKHT LSPQMHNEAF KALNLNFLYL PLEVAEESLP QAIYGLKAFN 

        70         80         90        100        110        120 
FRGINVTIPY KEKVFPFLDE VATEAKTIGA VNTIVHDRGR LIGYNTDAPG FLLSLKENDV 

       130        140        150        160        170        180 
EVTGKKVLLL GAGGAARAVA YALLTAGAEL IIANRTIDKA KELAKDFQGV GKISEILELG 

       190        200        210        220        230        240 
DKPISLAPYH MAVNTLPLGM HPYENQMPAV DFTGVTSDFV AYDLIYNPAE TKFLKASKEK 

       250        260        270        280 
GARTINGLSM LLWQGVLAFE KWTGVSPPVK VMKKAIGLSC 

Q3AEF5 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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