[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. STRAIN=Crossbred X Angus; TISSUE=Liver; NIH - Mammalian Gene Collection (MGC) project; Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: N⁶-(L-1,3-dicarboxypropyl)-L-lysine + NAD⁺ + H₂O = L-glutamate + 2-aminoadipate 6-semialdehyde + NADH.
PATHWAY: Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 2/6 .
SIMILARITY: Belongs to the saccharopine dehydrogenase family.

Copyright

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Cross-references

Sequence databases

EMBL

BC102545; AAI02546.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_001029460.1; -.

UniGene

Bt.27130

3D structure databases

ModBase

Q3T067.

Family and domain databases

InterPro

IPR016040; NAD(P)-bd.
IPR005097; Saccharopine_DHase.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.

Pfam

PF03435; Saccharop_dh; 1.
Pfam graphical view of domain structure.

BLOCKS

Q3T067.

Genome annotation databases

Ensembl

ENSBTAG00000003804; Bos taurus. [Contig view]

GeneID

507289; -.

KEGG

bta:507289; -.

Phylogenomic databases

HOVERGEN

Q3T067; -.

Other

ProtoNet

Q3T067.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 429`	`429`		`Probable saccharopine dehydrogenase.`	`PRO_0000290019`

Sequence information

Length: 429 AA [This is the length of the unprocessed precursor]

Molecular weight: 47320 Da [This is the MW of the unprocessed precursor]

CRC64: B989FF43A0887738 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MATQQRPFHL VVFGASGFTG QFVTEEVARE QVSPERTSHL PWAVAGRSRE KLLRVLERAA 

        70         80         90        100        110        120 
MKLGRPTLSS EVGIIICDIT NPASLDEMAK QATVVLNCVG PYRFYGEPVI KACIENGTSC 

       130        140        150        160        170        180 
IDISGEPQFL ELMYWKYHEK AAEKGVYIIG SSGFDSIPAD LGVIYTRNKM NGTLTAVESF 

       190        200        210        220        230        240 
LTISSGPEGL CVHDGTWKSA VYGFGDKSNL KKLRNESDMK PVPIVGPKLK RRWPISYCRE 

       250        260        270        280        290        300 
LNSYSIPFLG ADVSVVKRTQ RYLHENLEQS PVQYAAYINV GGITSVIKLM FAGLFFLFFV 

       310        320        330        340        350        360 
RFGIGRQLLI KFTWLFSFGY FSKQGPTQKQ IDASSFTMTF FGQGFSQGVS PVKNKPNIRI 

       370        380        390        400        410        420 
CTQVKGPEAG YVSTSIAMVQ AAMILLNDAS DLPKAGGVFT PGAAFSRTKL IDRLNEHGIE 


FSVISSTEV

Q3T067 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools