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UniProtKB/Swiss-Prot entry Q3Z990


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AROE_DEHE1
Primary accession number Q3Z990
Secondary accession numbers None
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on September 27, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 26)
Name and origin of the protein
Protein name Shikimate dehydrogenase
Synonym EC 1.1.1.25
Gene name
Name: aroE
OrderedLocusNames: DET0465
From
Dehalococcoides ethenogenes (strain 195) [TaxID: 243164] [HAMAP proteome]
Taxonomy Bacteria; Chloroflexi; Dehalococcoidetes; Dehalococcoides.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1102226; PubMed=15637277 [NCBI, ExPASy, EBI, Israel, Japan]
Seshadri R., Adrian L., Fouts D.E., Eisen J.A., Phillippy A.M., Methe B.A., Ward N.L., Nelson W.C., DeBoy R.T., Khouri H.M., Kolonay J.F., Dodson R.J., Daugherty S.C., Brinkac L.M., Sullivan S.A., Madupu R., Nelson K.E., Kang K.H., Impraim M., Tran K., Robinson J.M., Forberger H.A., Fraser C.M., Zinder S.H., Heidelberg J.F.;
"Genome sequence of the PCE-dechlorinating bacterium Dehalococcoides ethenogenes.";
Science 307:105-108(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000027; AAW40206.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_181209.1; -.
3D structure databases
ModBase Q3Z990.
Enzyme and pathway databases
BioCyc DETH243164:DET_0465-MON; -.
Ontologies
GO
GO:0004764; Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073; Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00222; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00507; aroE; 1.
BLOCKS Q3Z990.
Genome annotation databases
GeneID 3230170; -.
GenomeReviews CP000027_GR; DET0465.
KEGG det:DET0465; -.
NMPDR fig|243164.3.peg.727; -.
TIGR DET0465; -.
Phylogenomic databases
HOGENOM Q3Z990; -.
Other
ProtoNet Q3Z990.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   286  286     Shikimate dehydrogenase. PRO_1000058660
NP_BIND   130   134  5     NADP (By similarity). 
Sequence information
Length: 286 AA [This is the length of the unprocessed precursor] Molecular weight: 31194 Da [This is the MW of the unprocessed precursor] CRC64: 6ECE253437E7345F [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKTIPDALFG LIGFPVSHSV SPAMQNAAFK HCKLDYLYLT IAAKPEELQN VIASMGPLNI 

        70         80         90        100        110        120 
RGLNVTIPHK IEVIKYIDSL DPAAEKIGAV NTIVNENGRL KGYNTDFGGF VRLLEHNRIA 

       130        140        150        160        170        180 
PAKQRFTLLG AGGSAHAIAL AVCNLGGHLT VLARQEEKAK DLAGKMCLRL SGKTQGLELN 

       190        200        210        220        230        240 
DTNLEEALAD TDVIVNCTPV GMGNLAGQSL VPPRLLRPDL TVIDAIYNPC KTRLLEDAEK 

       250        260        270        280 
RGARIINGLE MLVWQGAMSF EIWTNQKAPF RLMMKEAELA LDENKK 

Q3Z990 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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