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UniProtKB/Swiss-Prot entry Q46046

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MBHL_CITFR
Primary accession number Q46046
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 41)
Name and origin of the protein
Protein name Hydrogenase-1 large chain
Synonyms HYD1
EC 1.12.99.6
Membrane-bound hydrogenase 1 large subunit
NiFe hydrogenase
Gene name
Name: hyaB
From
Citrobacter freundii [TaxID: 546] 
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Citrobacter.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Yano K., Ikebukuro K., Tomiyama M., Karube I.;
Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
D28594; BAA05930.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
HSSP P18188; 1FRF. [HSSP ENTRY / PDB]
ModBase Q46046.
Family and domain databases
InterPro IPR001501; Ni-dep_hyd_lsu.
Graphical view of domain structure.
Pfam PF00374; NiFeSe_Hases; 1.
Pfam graphical view of domain structure.
PROSITE PS00507; NI_HGENASE_L_1; 1.
PS00508; NI_HGENASE_L_2; 1.
BLOCKS Q46046.
Other
ProtoNet Q46046.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell membrane; Membrane; Metal-binding; Nickel; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   597  597     Hydrogenase-1 large chain. PRO_0000199711
METAL   76    76        Nickel (Potential). 
METAL   79    79        Nickel (Potential). 
METAL   576   576        Nickel (Potential). 
METAL   579   579        Nickel (Potential). 
Sequence information
Length: 597 AA [This is the length of the unprocessed precursor] Molecular weight: 66391 Da [This is the MW of the unprocessed precursor] CRC64: F9CCABD815D017F4 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSNSYQTQGY TVNNAGRRLV VDPITRIEGH MRCEVNIDEQ NIITNAVSCG TMFRGLEIIL 

        70         80         90        100        110        120 
QGRDPRDAWA FVERICGVCT GVHALASVYA IEDAIGIKVP DNANIIRNIM LATLWCHDHL 

       130        140        150        160        170        180 
VHFYQLAGMD WIDVLNALKA DPRATSQLAQ SLSAWPMSSP GYFFDVQNRL KKFVDGGQLG 

       190        200        210        220        230        240 
IFRNGYWGHP QYKLSPEANL MGFAHYLEAL DFQREIIKIH TVFGGKNPHP NWIVGGMPCA 

       250        260        270        280        290        300 
INIDQSGAVG AVDMERLNLV QSIITRTADF INNVMVPDAL AIGQFNKPWS QIGTGLSDKC 

       310        320        330        340        350        360 
VLSYGAFPDI ANDFSAKSLL MPGGAVINGD FNNVMPVDLA DQQQIQEFVD HAWYRYPDDQ 

       370        380        390        400        410        420 
LGRHPFEGIT EPWYNPGDVK GSDTDIQQLN EQERYSWIKA PRWRGHAMEV GPLARTLIAY 

       430        440        450        460        470        480 
HKGDAATIES VDRMMSALKL PLSGMQSTLG RILCRAHEAQ WAVSKLQYFF DKLMTNLKNG 

       490        500        510        520        530        540 
NLATANTEKW EPASWPQQCR GIGFTEAPRG ALGHWASIRD QKIDVYQCVV PTTWNASPRD 

       550        560        570        580        590 
PEGQIGAYEA ALMGTQMAIP DQPLEILRTL HSFDPCLACS THVLGDDGSE LIAVQVR
Q46046 in FASTA format

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