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UniProtKB/Swiss-Prot entry Q46AH5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G3P1_METBF
Primary accession number Q46AH5
Secondary accession numbers None
Integrated into Swiss-Prot on April 4, 2006
Sequence was last modified on September 13, 2005 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 26)
Name and origin of the protein
Protein name Glyceraldehyde-3-phosphate dehydrogenase 1
Synonyms GAPDH 1
EC 1.2.1.59
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase 1
Gene name
Name: gap1
OrderedLocusNames: Mbar_A2189
From
Methanosarcina barkeri (strain Fusaro / DSM 804) [TaxID: 269797] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.00810-06; PubMed=16980466 [NCBI, ExPASy, EBI, Israel, Japan]
Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R.;
"The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes.";
J. Bacteriol. 188:7922-7931(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000099; AAZ71117.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_305697.1; -.
3D structure databases
ModBase Q46AH5.
Enzyme and pathway databases
BioCyc MBAR269797:MBAR_A2189-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004365; Molecular function: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity (inferred from electronic annotation from HAMAP).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00559; -; 1.
PBIL [Tree]
InterPro IPR000173; GlycerAld_3-P_DHase.
IPR006436; Glyceraldehyde-3-P_DHase_2_arc.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
ProDom PD007761; GAPDH_like; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01546; GAPDH-II_archae; 1.
PROSITE PS00071; GAPDH; 1.
BLOCKS Q46AH5.
Genome annotation databases
GeneID 3626065; -.
GenomeReviews CP000099_GR; Mbar_A2189.
KEGG mba:Mbar_A2189; -.
NMPDR fig|269797.3.peg.1766; -.
Phylogenomic databases
HOGENOM Q46AH5; -.
Genome annotation databases
CMR Q46AH5; Mbar_A2189.
Other
ProtoNet Q46AH5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; NAD; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   338  338     Glyceraldehyde-3-phosphate dehydrogenase 1. PRO_0000232390
NP_BIND   13    14  2     NAD (By similarity). 
REGION   140   142  3     Glyceraldehyde 3-phosphate binding (By similarity). 
REGION   195   196  2     Glyceraldehyde 3-phosphate binding (By similarity). 
ACT_SITE   141   141        Nucleophile (By similarity). 
BINDING   111   111        NAD; via amide nitrogen (By similarity). 
BINDING   169   169        NAD (By similarity). 
BINDING   300   300        NAD; via carbonyl oxygen (By similarity). 
Sequence information
Length: 338 AA [This is the length of the unprocessed precursor] Molecular weight: 36958 Da [This is the MW of the unprocessed precursor] CRC64: 0C51D7380992EA43 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVKAKIAVNG YGTIGKRVAD AVRAQDDMEV IGISKTKPNY EAAVAHQIGY DIYAPAANLE 

        70         80         90        100        110        120 
AFEKAGMPAA GTIEEMVEKA DLVVDCTPGG IGEKNKPMYE KAGVKAIWQG GEDHSLAGFS 

       130        140        150        160        170        180 
FNAICNYEQA VGRDLVRVVS CNTTALCRAI YPIDKELGVK KARVVLARRA TDPNDVKKGP 

       190        200        210        220        230        240 
INAIVPDPIK LPSHHGPDVK SVLPQINITS AALKIPTTLM HVHTVNMEVE KDCTVDDVKN 

       250        260        270        280        290        300 
IFGSQPRIRF VGQGMSSTAE IMEFARDMKR PRNDMWENCI WPESITVGDK ELYFFQAVHQ 

       310        320        330 
ESIVVPENVD AIRAMMEFES DGAKSIEKTN KAIGLSKK
Q46AH5 in FASTA format

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