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UniProtKB/Swiss-Prot entry Q47ZE0


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name FOLD1_COLP3
Primary accession number Q47ZE0
Secondary accession numbers None
Integrated into Swiss-Prot on December 12, 2006
Sequence was last modified on September 13, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 19)
Name and origin of the protein
Protein name Bifunctional protein folD 1
Synonyms None
Includes Methylenetetrahydrofolate dehydrogenase
     (EC 1.5.1.5)
Methenyltetrahydrofolate cyclohydrolase
     (EC 3.5.4.9)
Gene name
Name: folD1
OrderedLocusNames: CPS_3133
From
Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) [TaxID: 167879] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales; Colwelliaceae; Colwellia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0504766102; PubMed=16043709 [NCBI, ExPASy, EBI, Israel, Japan]
Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X., Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M., Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A., Zhou L., Davidsen T.M., Wu M., Huston A.L., Lewis M., Weaver B., Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M.;
"The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses.";
Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000083; AAZ27235.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_269830.1; -.
3D structure databases
ModBase Q47ZE0.
Enzyme and pathway databases
BioCyc CPSY167879:CPS_3133-MON; -.
Ontologies
GO
GO:0004477; Molecular function: methenyltetrahydrofolate cyclohydrolase activity (inferred from electronic annotation from HAMAP).
GO:0004488; Molecular function: methylenetetrahydrofolate dehydrogenase (NADP+) activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01576; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR000672; THF_DHase/CycOHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00763; THF_DHG_CYH; 1.
PF02882; THF_DHG_CYH_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00085; THFDHDRGNASE.
ProDom PD002300; THFDhg/Cyc_hydro; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00766; THF_DHG_CYH_1; FALSE_NEG.
PS00767; THF_DHG_CYH_2; 1.
BLOCKS Q47ZE0.
Genome annotation databases
GeneID 3521491; -.
GenomeReviews CP000083_GR; CPS_3133.
KEGG cps:CPS_3133; -.
NMPDR fig|167879.3.peg.2562; -.
TIGR CPS_3133; -.
Phylogenomic databases
HOGENOM Q47ZE0; -.
Other
ProtoNet Q47ZE0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Histidine biosynthesis; Hydrolase; Methionine biosynthesis; Multifunctional enzyme; NADP; One-carbon metabolism; Oxidoreductase; Purine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   282  282     Bifunctional protein folD 1. PRO_0000268321
Sequence information
Length: 282 AA [This is the length of the unprocessed precursor] Molecular weight: 30433 Da [This is the MW of the unprocessed precursor] CRC64: 0C3FF2EA50C87F4F [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSALILDGKS VTKKSEEDLR SRVARLKELS NGAVPILATI LVGNDPSSAT YVKMKSNACT 

        70         80         90        100        110        120 
RVGMDSLKVE MSEETTTEEL LAEIAKLNAN PNIHGILLQH PVPPQINERQ CFDSIDLSKD 

       130        140        150        160        170        180 
VDGVTCWGFG RMAMNETSYG SATPKGIIRI LEAYDIQLEG KHAVVVGRSP ILGKPMAMML 

       190        200        210        220        230        240 
LNKNCTVTIC HSKTVGLDKI IKTADIVVGA VGKPEFIKAD WIKDDAVVID AGYHEGGIGD 

       250        260        270        280 
IELQPLMSRV KAYTPVPGGV GPMTINTLIY QTVEACELKL AQ 

Q47ZE0 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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