NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 29715 / DSM 3756 / IFO 14741 / JCM 8877 / NCMB 2082;
DOI=10.1007/BF00017803; PubMed=8616244 [NCBI, ExPASy, EBI, Israel, Japan]
Brinkmann H., Martin W.;
"Higher-plant chloroplast and cytosolic 3-phosphoglycerate kinases: a case of endosymbiotic gene replacement.";
Plant Mol. Biol. 30:65-75(1996).

Comments

CATALYTIC ACTIVITY: D-glyceraldehyde 3-phosphate + phosphate + NAD(P)⁺ = 3-phospho-D-glyceroyl phosphate + NAD(P)H.
PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5 .
SUBUNIT: Homotetramer (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

L47295; AAB03730.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S65043; S65043.

3D structure databases

HSSP

P00362; 1NQO. [HSSP ENTRY / SWISS-3DIMAGE / PDB]

ModBase

Q48335.

Family and domain databases

InterPro

IPR000173; GlycerAld_3-P_DHase.
IPR006424; Glyceraldehyde-3-P_DHase_1.
Graphical view of domain structure.

PANTHER

PTHR10836; GAP_DH; 1.

Pfam

PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000149; GAP_DH; 1.

PRINTS

PR00078; G3PDHDRGNASE.

TIGRFAMs

TIGR01534; GAPDH-I; 1.

PS00071; GAPDH; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Cytoplasm; Glycolysis; NAD; NADP; Oxidoreductase.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 335`	`335`	`Glyceraldehyde-3-phosphate dehydrogenase.`	`PRO_0000145739`
`NP_BIND`	`15 16`	`2`	`NAD (By similarity).`
`REGION`	`155 157`	`3`	`Glyceraldehyde 3-phosphate binding (By similarity).`
`REGION`	`214 215`	`2`	`Glyceraldehyde 3-phosphate binding (By similarity).`
`ACT_SITE`	`156 156`		`Nucleophile (By similarity).`
`BINDING`	`37 37`		`NAD (By similarity).`
`BINDING`	`186 186`		`Glyceraldehyde 3-phosphate (By similarity).`
`BINDING`	`201 201`		`Glyceraldehyde 3-phosphate (By similarity).`
`BINDING`	`237 237`		`Glyceraldehyde 3-phosphate (By similarity).`
`BINDING`	`301 301`		`NAD; via carbonyl oxygen (By similarity).`
`BINDING`	`318 318`		`NAD (By similarity).`

Sequence information

Length: 335 AA [This is the length of the unprocessed precursor]

Molecular weight: 35941 Da [This is the MW of the unprocessed precursor]

CRC64: F25BF308255E03BB [This is a checksum on the sequence]

        10         20         30         40         50         60 
MMSEPVRVGL NGFGRIGRNV FRASLHSDDV EIVGINDVMD DSEIDYFAQY DSVMGELEGA 

        70         80         90        100        110        120 
SVDDGVLTVD GTDFEAGIFH ETDPTQLPWD DLDVDVAFEA TGIFRTKEDA SQHLDAGADK 

       130        140        150        160        170        180 
VLISAPPKGD EPVKQLVYGV NHDEYDGEDV VSNASCTTNS ITPVAKVLDE EFGINAGQLT 

       190        200        210        220        230        240 
TVHAYTGSQN LMDGPNGKPR RRRAAAENII PTSTGAAQAA TEVLPELEGK LDGMAIRVPV 

       250        260        270        280        290        300 
PNGSITEFVV DLDDDVTESD VNAAFEDAAA GELEGVLGVT SDDVVSSDIL GDPYSTQVDL 

       310        320        330 
QSTNVVSGMT KILTWYDNEY GFSNRMLDVA EYITE

Q48335 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools