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UniProtKB/Swiss-Prot entry Q48943


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name FMDC_METBF
Primary accession number Q48943
Secondary accession number Q46CY9
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 59)
Name and origin of the protein
Protein name Molybdenum-containing formylmethanofuran dehydrogenase 1 subunit C
Synonyms EC 1.2.99.5
Molybdenum-containing formylmethanofuran dehydrogenase I subunit C
Gene name
Name: fmdC
OrderedLocusNames: Mbar_A1290
From
Methanosarcina barkeri (strain Fusaro / DSM 804) [TaxID: 269797] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-23.
PubMed=8617280 [NCBI, ExPASy, EBI, Israel, Japan]
Vorholt J.A., Vaupel M., Thauer R.K.;
"A polyferredoxin with eight [4Fe-4S] clusters as a subunit of molybdenum formylmethanofuran dehydrogenase from Methanosarcina barkeri.";
Eur. J. Biochem. 236:309-317(1996).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.00810-06; PubMed=16980466 [NCBI, ExPASy, EBI, Israel, Japan]
Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R.;
"The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes.";
J. Bacteriol. 188:7922-7931(2006).
[3]
SUBSTRATE SPECIFICITY.
PubMed=8125106 [NCBI, ExPASy, EBI, Israel, Japan]
Bertram P.A., Karrach M., Schmitz R.A., Boecher R., Albracht S.P.J., Thauer R.K.;
"Formylmethanofuran dehydrogenases from methanogenic Archaea. Substrate specificity, EPR properties and reversible inactivation by cyanide of the molybdenum or tungsten iron-sulfur proteins.";
Eur. J. Biochem. 220:477-484(1994).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X93084; CAA63631.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
CP000099; AAZ70253.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S62199; S62199.
RefSeq YP_304833.1; -.
3D structure databases
ModBase Q48943.
Enzyme and pathway databases
BioCyc MBAR269797:MBAR_A1290-MON; -.
Family and domain databases
InterPro IPR017550; Formylmethanofuran_DH_C.
IPR002489; Glu_synthase_C.
Graphical view of domain structure.
Gene3D G3DSA:2.160.20.60; Glu_synthase_C; 1.
Pfam PF01493; GXGXG; 1.
Pfam graphical view of domain structure.
BLOCKS Q48943.
Genome annotation databases
GeneID 3627699; -.
GenomeReviews CP000099_GR; Mbar_A1290.
KEGG mba:Mbar_A1290; -.
NMPDR fig|269797.3.peg.1295; -.
Phylogenomic databases
HOGENOM Q48943; -.
Genome annotation databases
CMR Q48943; Mbar_A1290.
Other
ProtoNet Q48943.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Direct protein sequencing; Methanogenesis; Molybdenum; Oxidoreductase; Repeat.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   301  301     Molybdenum-containing formylmethanofuran dehydrogenase 1 subunit C. PRO_0000144190
REPEAT   112   124  13     1. 
REPEAT   131   143  13     2. 
REPEAT   150   162  13     3. 
REPEAT   176   188  13     4. 
REPEAT   195   207  13     5. 
REPEAT   214   226  13     6. 
REPEAT   233   245  13     7. 
REGION   112   245  134     7 X 13 AA repeats of [GW]-X-X-[MQ]-X-X-G-X-[IL]-X-[IV]-X-G. 
CONFLICT   2     2        Missing (in Ref. 1; AA sequence). 
Sequence information
Length: 301 AA [This is the length of the unprocessed precursor] Molecular weight: 31551 Da [This is the MW of the unprocessed precursor] CRC64: D871C80B50AC000D [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTEGVLINEN EVESKLEAVI KPGSFTGENA GEMAEVILIP KKAIDIKLEA DVITPDSFAG 

        70         80         90        100        110        120 
KSAEEIGKLS VWQGPKTYPL SEFFEVTGNG GSSAAETLIR IKGDAMRIKR IGESMSAGKI 

       130        140        150        160        170        180 
EIEGSAGMHV GTGMKGGELV VYGDADSWAG MEMTGGLLHI KGNAGDHVGC AYRGKWHGMK 

       190        200        210        220        230        240 
GGRIVIEGSA RHQLGGGMDG GEILVEGDVK SFCGIRQNGG LIFVKGSALR GVGAEMAGGT 

       250        260        270        280        290        300 
IVIGGKIERF SPGFEFVSME NSITSGEVEL IGEFKKFTGD YAISKRAKGA LYVVADTNPE 


L 

Q48943 in FASTA format

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