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UniProtKB/Swiss-Prot entry Q49617


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NADB_MYCLE
Primary accession number Q49617
Secondary accession number Q9CC64
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on April 27, 2001 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 57)
Name and origin of the protein
Protein name L-aspartate oxidase
Synonyms LASPO
EC 1.4.3.16
Quinolinate synthetase B
Gene name
Name: nadB
OrderedLocusNames: ML1226
ORFNames: B1170_C1_167
From
Mycobacterium leprae [TaxID: 1769] [HAMAP proteome]
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Mycobacteriaceae; Mycobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Smith D.R., Robison K.;
Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=TN;
DOI=10.1038/35059006; PubMed=11234002 [NCBI, ExPASy, EBI, Israel, Japan]
Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R., Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E., Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N., Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S., Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R., Barrell B.G.;
"Massive gene decay in the leprosy bacillus.";
Nature 409:1007-1011(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U00010; AAA17059.1; ALT_FRAME; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AL583921; CAC31607.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR D87062; D87062.
S72695; S72695.
RefSeq NP_301888.1; -.
3D structure databases
HSSP P10902; 1CHU. [HSSP ENTRY / PDB]
ModBase Q49617.
Enzyme and pathway databases
BioCyc MLEP272631:ML1226-MON; -.
Organism-specific databases
Leproma ML1226; -.
Family and domain databases
InterPro IPR003953; FAD_bind2_N.
IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR004112; Fum_Rdtase/Succ_DHase_flav_C.
IPR005288; NadB.
IPR001100; Pyr_nuc-diS_OxRdtase.
Graphical view of domain structure.
Pfam PF00890; FAD_binding_2; 1.
PF02910; Succ_DH_flav_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00368; FADPNR.
PR00411; PNDRDTASEI.
TIGRFAMs TIGR00551; nadB; 1.
BLOCKS Q49617.
Genome annotation databases
GeneID 910334; -.
GenomeReviews AL450380_GR; ML1226.
KEGG mle:ML1226; -.
NMPDR fig|272631.1.peg.760; -.
Phylogenomic databases
HOGENOM Q49617; -.
Genome annotation databases
CMR Q49617; ML1226.
Other
ProtoNet Q49617.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; FAD; Flavoprotein; Oxidoreductase; Pyridine nucleotide biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   526  526     L-aspartate oxidase. PRO_0000184388
NP_BIND   13    27  15     FAD (Potential). 
ACT_SITE   234   234        By similarity. 
ACT_SITE   257   257        By similarity. 
Sequence information
Length: 526 AA [This is the length of the unprocessed precursor] Molecular weight: 54182 Da [This is the MW of the unprocessed precursor] CRC64: A90A6EC4332C248D [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAVPDWKHAA DVVVIGTGVA GLAAALAAHR AGRNVVVLTK ADQRRGETAT HYAQGGIAVV 

        70         80         90        100        110        120 
LPGSDDSVDA HASDTLAAGA GMCNLDTVYS IVAEGYHAVT ELVGYGARFD ESIPGRWAVT 

       130        140        150        160        170        180 
CEGGHSRRRI VHAGGDATGA EVQRALDHAA DVLDIRTSHL ALRVLHDGTV VNGVSVLNPN 

       190        200        210        220        230        240 
GWGIVSAPSV ILASGGLGHL YGATTNPEGS TGDGIALALW AGVAVSDLEF IQFHPTMLFA 

       250        260        270        280        290        300 
AGTGTGGRRP LVTEAIRGEG AILLDSKGNS VTSGVHPLGD LAPRDVVAAA IDARLKATGD 

       310        320        330        340        350        360 
SCVYLDARGI DGFASRFPTV TAACRTVGID PAREPIPVVP GAHYSCGGIV TDAYGQTELA 

       370        380        390        400        410        420 
GLFAAGEVAR TGMHGANRLA SNSLLEGLVV GGRAGRAAAA HAAAAGRAYV SKLEPVTHHA 

       430        440        450        460        470        480 
LKRRELQRVM SRDAAVMRNA AGLQRLSDTL AEAPIRHVTG RRDFEDVALT LTARAVAAAA 

       490        500        510        520 
LARNESRGCH HCTEYPDTAP EHARSTVIRL ADDQNLVRAE ALATVG 

Q49617 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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