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UniProtKB/Swiss-Prot entry Q4L966

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ROCA_STAHJ
Primary accession number Q4L966
Secondary accession numbers None
Integrated into Swiss-Prot on November 22, 2005
Sequence was last modified on August 2, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 23)
Name and origin of the protein
Protein name 1-pyrroline-5-carboxylate dehydrogenase
Synonyms P5C dehydrogenase
EC 1.5.1.12
Gene name
Name: rocA
OrderedLocusNames: SH0500
From
Staphylococcus haemolyticus (strain JCSC1435) [TaxID: 279808] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Staphylococcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.187.21.7292-7308.2005; PubMed=16237012 [NCBI, ExPASy, EBI, Israel, Japan]
Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y., Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C., Hiramatsu K.;
"Whole-genome sequencing of Staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species.";
J. Bacteriol. 187:7292-7308(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AP006716; BAE03809.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_252415.1; -.
3D structure databases
ModBase Q4L966.
Enzyme and pathway databases
BioCyc SHAE279808:SH0500-MON; -.
Ontologies
GO
GO:0003842; Molecular function: 1-pyrroline-5-carboxylate dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0006537; Biological process: glutamate biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00733; -; 1.
PBIL [Tree]
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR005932; d-1-pyrroline-5-COlate_DHase-2.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01237; D1pyr5carbox2; 1.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
BLOCKS Q4L966.
Genome annotation databases
GeneID 3481891; -.
GenomeReviews AP006716_GR; SH0500.
KEGG sha:SH0500; -.
NMPDR fig|279808.3.peg.589; -.
Phylogenomic databases
HOGENOM Q4L966; -.
Genome annotation databases
CMR Q4L966; SH0500.
Other
ProtoNet Q4L966.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   514  514     1-pyrroline-5-carboxylate dehydrogenase. PRO_0000056522
ACT_SITE   286   286        By similarity. 
ACT_SITE   320   320        By similarity. 
Sequence information
Length: 514 AA [This is the length of the unprocessed precursor] Molecular weight: 56597 Da [This is the MW of the unprocessed precursor] CRC64: 41AAD6873F1C7C86 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVVPFKNEPG IDFSVQENVE RFQKTLEQVK NELGQTLPIV IDGEHITKDD TFDSINPANT 

        70         80         90        100        110        120 
SELIAKVSKA TKEDVDKAFE SSNKAYKAWR QWSHKDRAEL LLRVAAIIRR RKEEISAVMV 

       130        140        150        160        170        180 
YEAGKPWDEA VGDAAEGIDF IEYYARSMME LADGKPVLDR EGEHNKYFYK SIGTGVTIPP 

       190        200        210        220        230        240 
WNFPFAIMAG TTLAPVVAGN TVLLKPAEDT VLTAYKLIEI LEEAGLPKGV VNFVPGDPKE 

       250        260        270        280        290        300 
IGDYLVDSVH THFVTFTGSR ATGTRIYERS AVVQEGQTFL KRVIAEMGGK DAIVVDENID 

       310        320        330        340        350        360 
TDLAAESIIT SAFGFSGQKC SACSRAIVHS SVYDEVLEKA VALTKELTVG NTVDNTFMGP 

       370        380        390        400        410        420 
VINKKQFDKI KKYIEIGGKE GKIEIGGEAD DSTGYFIKPT IISGLKSSDQ VMQEEIFGPV 

       430        440        450        460        470        480 
VGFTKFDNFE EAIEIANDTD YGLTGAVITN NRENWIKAVN EFDVGNLYLN RGCTAAVVGY 

       490        500        510 
HPFGGFKMSG TDAKTGSPDY LLNFLEQKVV SEMF
Q4L966 in FASTA format

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