ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q50501


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name MTD_METTH
Primary accession number Q50501
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    July 22, 2008 (Entry version 55)
Name and origin of the protein
Protein name F420-dependent methylenetetrahydromethanopterin dehydrogenase
Synonyms MTD
EC 1.5.99.9
Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase
Gene name
Name: mtd
OrderedLocusNames: MTH_1464
From
Methanobacterium thermoautotrophicum [TaxID: 187420] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Methanobacteria; Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=Delta H;
PubMed=7730278 [NCBI, ExPASy, EBI, Israel, Japan]
Noelling J., Pihl T.D., Vriesema A., Reeve J.N.;
"Organization and growth phase-dependent transcription of methane genes in two regions of the Methanobacterium thermoautotrophicum genome.";
J. Bacteriol. 177:2460-2468(1995).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Delta H;
PubMed=9371463 [NCBI, ExPASy, EBI, Israel, Japan]
Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R., Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N.;
"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics.";
J. Bacteriol. 179:7135-7155(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U19362; AAA87412.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE000666; AAB85939.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A69062; A69062.
RefSeq NP_276578.1; -.
3D structure databases
ModBase Q50501.
Enzyme and pathway databases
BioCyc MTHE187420:MTH1464-MON; -.
Ontologies
GO
GO:0030268; Molecular function: methylenetetrahydromethanopterin dehydrogenase activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00058; -; 1.
PBIL [Tree]
InterPro IPR002844; Methylene_DHase.
Graphical view of domain structure.
Pfam PF01993; MTD; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF005627; MTD; 1.
BLOCKS Q50501.
Genome annotation databases
GeneID 1471733; -.
GenomeReviews AE000666_GR; MTH_1464.
KEGG mth:MTH1464; -.
NMPDR fig|187420.1.peg.1433; -.
Phylogenomic databases
HOGENOM Q50501; -.
Genome annotation databases
CMR Q50501; MTH_1464.
Other
ProtoNet Q50501.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Methanogenesis; One-carbon metabolism; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
INIT_MET   1     1        Removed (By similarity). 
CHAIN   2   276  275     F420-dependent methylenetetrahydromethanopterin dehydrogenase. PRO_0000075041
Sequence information
Length: 276 AA [This is the length of the unprocessed precursor] Molecular weight: 29601 Da [This is the MW of the unprocessed precursor] CRC64: 18445E608FEE8457 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MVVKIGIIRC GNIGTSPVLD LLLDERADRP NIDVCVVGSG AKMNPDEIER AVPTMLEMDR 

        70         80         90        100        110        120 
DFVIFISPNP GAPGPAKARE LLSEADVPAM IIGDAPGLRV KDEIEEQGLG YIIVKADPMI 

       130        140        150        160        170        180 
GARREFLDPT EMASFNSDVI KVLAFTGAYR VVQNTIDAMI ADVEAGKAPE LPQVVIDTDV 

       190        200        210        220        230        240 
AVEAAGYENP YAKAKAMAAY EIATKVADID VKGCFMVQDP DKYIPIVASA HEMLAAAAKL 

       250        260        270 
AVEAREIEKA NDTVLRTPHG KEGETLSKTD LLAKPE 

Q50501 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ca flag CBR Canada Mirror sites: Australia  Brazil  China  Korea  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!