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UniProtKB/Swiss-Prot entry Q51363


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NADB_PSEAE
Primary accession number Q51363
Secondary accession number Q51412
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on November 1, 1997 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 57)
Name and origin of the protein
Protein name L-aspartate oxidase
Synonyms LASPO
EC 1.4.3.16
Quinolinate synthetase B
Gene name
Name: nadB
OrderedLocusNames: PA0761
From
Pseudomonas aeruginosa [TaxID: 287] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=FRD1;
DOI=10.1016/0378-1119(95)00028-5; PubMed=7737518 [NCBI, ExPASy, EBI, Israel, Japan]
DeVries C.A., Hassett D.J., Flynn J.L., Ohman D.E.;
"Genetic linkage in Pseudomonas aeruginosa of algT and nadB: mutation in nadB does not affect NAD biosynthesis or alginate production.";
Gene 156:63-67(1995).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228;
DOI=10.1038/35023079; PubMed=10984043 [NCBI, ExPASy, EBI, Israel, Japan]
Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M., Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.";
Nature 406:959-964(2000).
[3]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-31.
STRAIN=FRD1;
PubMed=7961421 [NCBI, ExPASy, EBI, Israel, Japan]
Devries C.A., Ohman D.E.;
"Mucoid-to-nonmucoid conversion in alginate-producing Pseudomonas aeruginosa often results from spontaneous mutations in algT, encoding a putative alternate sigma factor, and shows evidence for autoregulation.";
J. Bacteriol. 176:6677-6687(1994).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U17232; AAA92356.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE004091; AAG04150.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
L36379; AAA64438.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T46863; T46863.
RefSeq NP_249452.1; -.
3D structure databases
HSSP P10902; 1CHU. [HSSP ENTRY / PDB]
ModBase Q51363.
Enzyme and pathway databases
BioCyc PAER208964:PA0761-MON; -.
Organism-specific databases
PseudoCAP PA0761; -.
Family and domain databases
InterPro IPR003953; FAD_bind2_N.
IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR004112; Fum_Rdtase/Succ_DHase_flav_C.
IPR005288; NadB.
IPR003042; Rng_hydrolase.
Graphical view of domain structure.
Pfam PF00890; FAD_binding_2; 1.
PF02910; Succ_DH_flav_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00368; FADPNR.
PR00420; RNGMNOXGNASE.
TIGRFAMs TIGR00551; nadB; 1.
BLOCKS Q51363.
Genome annotation databases
GeneID 882067; -.
GenomeReviews AE004091_GR; PA0761.
KEGG pae:PA0761; -.
Phylogenomic databases
HOGENOM Q51363; -.
Other
LinkHub Q51363; -.
Genome annotation databases
CMR Q51363; PA0761.
Other
ProtoNet Q51363.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; FAD; Flavoprotein; Oxidoreductase; Pyridine nucleotide biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   538  538     L-aspartate oxidase. PRO_0000184393
NP_BIND   10    24  15     FAD (Potential). 
ACT_SITE   244   244        By similarity. 
ACT_SITE   263   263        By similarity. 
Sequence information
Length: 538 AA [This is the length of the unprocessed precursor] Molecular weight: 60005 Da [This is the MW of the unprocessed precursor] CRC64: F2B76A500DA814A1 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSQHYQHDVL VIGSGAAGLS LALTLPEHLR IAVLSKGELS QGSTYWAQGG VAAVLDDTDT 

        70         80         90        100        110        120 
VESHVEDTLV AGGGLCREDA VRFTVEHSRE AIQWLIEQGV PFTRDEQHNH EEGSFEYHLT 

       130        140        150        160        170        180 
REGGHSHRRI IHAADATGAA IFNTLLAQAR RRPNIELLSQ RVAVDLITER KLGLPSKRCL 

       190        200        210        220        230        240 
GAYVLNRESG EVDTFRARFS VLASGGASKV YLYTSNPDGN SGDGIAMAWR AGCRVGNLEF 

       250        260        270        280        290        300 
NQFHPTCLYH PQAKSFLITE ALRGEGALLR LPNGERFMPR FDPRGELAPR DIVARAIDHE 

       310        320        330        340        350        360 
MKRLGIDCVY LDISHKPAEF IKAHFPTVYE RCLDFGIDIT QQPIPVVPAA HYTCGGVLVD 

       370        380        390        400        410        420 
QHGHTDVPGL YAIGETTFTG LHGANRMASN SLLECFVYAR SAAADMLQRL PGTPVPESLP 

       430        440        450        460        470        480 
SWDASQVTDS DEDVIIAHNW DELRRFMWDY VGIVRTNKRL QRAQHRVRLL LSEIDEFYSN 

       490        500        510        520        530 
YKVSRDLIEL RNLALVAELI IRSAMQRRES RGLHYTLDYP DLLPEARDTI LVPPIYGD 

Q51363 in FASTA format

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View entry in raw text format (no links)
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