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UniProtKB/Swiss-Prot entry Q51799


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PORC_PYRFU
Primary accession number Q51799
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on November 1, 1996 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 53)
Name and origin of the protein
Protein name Pyruvate/ketoisovalerate oxidoreductases common subunit gamma
Synonyms None
Includes Pyruvate synthase subunit porC
     (EC 1.2.7.1)
     (Pyruvate oxidoreductase gamma chain)
     (POR)
     (Pyruvic-ferredoxin oxidoreductase subunit gamma)
Ketoisovalerate oxidoreductase subunit vorC
     (VOR)
     (EC 1.2.7.7)
     (2-oxoisovalerate oxidoreductase gamma chain)
     (2-oxoisovalerate ferredoxin reductase subunit gamma)
Gene name
Name: porG
OrderedLocusNames: PF0971
From
Pyrococcus furiosus [TaxID: 2261] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-28.
STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
PubMed=8550425 [NCBI, ExPASy, EBI, Israel, Japan]
Kletzin A., Adams M.W.W.;
"Molecular and phylogenetic characterization of pyruvate and 2-ketoisovalerate ferredoxin oxidoreductases from Pyrococcus furiosus and pyruvate ferredoxin oxidoreductase from Thermotoga maritima.";
J. Bacteriol. 178:248-257(1996).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
Weiss R.B., Dunn D.M., Robb F.T., Brown J.R.;
"The complete sequence of the Pyrococcus furiosus genome.";
Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.
[3]
CHARACTERIZATION.
STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
DOI=10.1016/0167-4838(93)90190-3; PubMed=8380721 [NCBI, ExPASy, EBI, Israel, Japan]
Blamey J.M., Adams M.W.W.;
"Purification and characterization of pyruvate ferredoxin oxidoreductase from the hyperthermophilic archaeon Pyrococcus furiosus.";
Biochim. Biophys. Acta 1161:19-27(1993).
Comments
  • CATALYTIC ACTIVITY: Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
  • CATALYTIC ACTIVITY: 3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + 2 reduced ferredoxin + H+.
  • SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma chain.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X85250; CAA59500.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE010209; AAL81095.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T45083; T45083.
RefSeq NP_578700.1; -.
3D structure databases
ModBase Q51799.
Family and domain databases
InterPro IPR011894; PorC_KorC.
IPR002869; Pyrv_Fd/Flavodoxin_OxRdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.920.10; Pyrv_Fd/Flavodoxin_OxRdtase; 1.
Pfam PF01558; POR; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR02175; PorC_KorC; 1.
BLOCKS Q51799.
Genome annotation databases
GeneID 1468836; -.
GenomeReviews AE009950_GR; PF0971.
KEGG pfu:PF0971; -.
NMPDR fig|186497.1.peg.1007; -.
Phylogenomic databases
HOGENOM Q51799; -.
Genome annotation databases
CMR Q51799; PF0971.
Other
ProtoNet Q51799.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Direct protein sequencing; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   185  185     Pyruvate/ketoisovalerate oxidoreductases common subunit gamma. PRO_0000099914
Sequence information
Length: 185 AA [This is the length of the unprocessed precursor] Molecular weight: 20021 Da [This is the MW of the unprocessed precursor] CRC64: E58743586CE87C13 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MIEVRFHGRG GQGAVTAANI LAEAAFLEGK YVQAFPFFGV ERRGAPVTAF TRIDNKPIRI 

        70         80         90        100        110        120 
KTQIYEPDVV VVLDPSLLDA VDVTAGLKDE GIVIVNTEKS KEEVLEKLKK KPKKLAIVDA 

       130        140        150        160        170        180 
TTIALEILGL PITNTAILGA VAKATGLVKI ESIEEAIKDT FSGELGEKNA RAAREAYEKT 


EVFEL 

Q51799 in FASTA format

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