ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q54RA2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name AL4A1_DICDI
Primary accession number Q54RA2
Secondary accession numbers None
Integrated into Swiss-Prot on July 1, 2008
Sequence was last modified on May 24, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 20)
Name and origin of the protein
Protein name Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [Precursor]
Synonyms P5C dehydrogenase
EC 1.5.1.12
Aldehyde dehydrogenase family 4 member A1 homolog
Gene name
ORFNames: DDB_0229934
From
Dictyostelium discoideum (Slime mold) [TaxID: 44689] 
Taxonomy Eukaryota; Mycetozoa; Dictyosteliida; Dictyostelium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature03481; PubMed=15875012 [NCBI, ExPASy, EBI, Israel, Japan]
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
"The genome of the social amoeba Dictyostelium discoideum.";
Nature 435:43-57(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AAFI02000052; EAL65787.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_639145.1; -.
3D structure databases
ModBase Q54RA2.
Organism-specific databases
dictyBase DDB0229934; geneDDB0229934.
Family and domain databases
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR005931; d-1-pyrroline-5-COlate_DHase-1.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01236; D1pyr5carbox1; 1.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
BLOCKS Q54RA2.
Genome annotation databases
GeneID 3390723; -.
KEGG ddi:DDB_0229934; -.
Other
ProtoNet Q54RA2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Mitochondrion; NAD; Oxidoreductase; Proline metabolism; Transit peptide.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1     ?        Mitochondrion (Potential). 
CHAIN   ?   558        Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial. PRO_0000342183
NP_BIND   286   291  6     NAD (By similarity). 
ACT_SITE   306   306        By similarity. 
ACT_SITE   340   340        By similarity. 
Sequence information
Length: 558 AA [This is the length of the unprocessed precursor] Molecular weight: 61633 Da [This is the MW of the unprocessed precursor] CRC64: 6F6ACCB3479EB1AA [This is a checksum on the sequence]
        10         20         30         40         50         60 
MLRNTSRVLM SHFARANIPT PVNQPMLNYE VGSTHRKLLK EACAKFRNTT IDIPCVVGGK 

        70         80         90        100        110        120 
EIRTGDVQKQ LICSDHNKVL ATFHQANAEL LKLAVENSME SKAQWESLPF EARSAVFLKA 

       130        140        150        160        170        180 
ADLLNTKYRY DVLASTMLGQ GKTVWQAEID AAAEGIDFLR FNVKYAQEIY QQQPPANSAG 

       190        200        210        220        230        240 
CWNILTYQPL EGYVVAISPF NFTAIGLNLS SAPALMGNVV LWKPASTAVL SNWIVYKALL 

       250        260        270        280        290        300 
EAGLPAGVIQ FLPGSGRLVG EHLFNNRNFS GLHFTGSTGV FNDIYKKTAD NLVAGVYKGY 

       310        320        330        340        350        360 
PRIVGETGGK DFHFLHNSGD VENFVNNTLR GAFEYQGQKC SACSRAYIPQ SLWPQIKDRL 

       370        380        390        400        410        420 
VTGVKSMKMG QSDDFSSFVS AVIDKNSFNN IQSYIEHAKA SPDAEIIVGG KCDSSVGWFV 

       430        440        450        460        470        480 
EPTIILAKDP HYKSMEEEIF GPVLTIYVYE DSKFEETLKI CDETSPYALT GSIFSTCRYA 

       490        500        510        520        530        540 
IETAHKYLKN AAGNFYINDK CTGAVVGQQP FGGSRASGTN DKAGSSLNLL RWISARTIKE 

       550 
NFVPLTSFTY PYMIDPEN 

Q54RA2 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ca flag CBR Canada Mirror sites: Australia  Brazil  China  Korea  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!