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UniProtKB/Swiss-Prot entry Q58065


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NAOX_METJA
Primary accession number Q58065
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1997
Sequence was last modified on March 1, 2005 (Sequence version 2)
Annotations were last modified on    September 2, 2008 (Entry version 58)
Name and origin of the protein
Protein name Putative NADH oxidase
Synonyms NOXase
EC 1.6.99.3
Gene name
OrderedLocusNames: MJ0649
From
Methanocaldococcus jannaschii (Methanococcus jannaschii) [TaxID: 2190] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Methanococci; Methanococcales; Methanocaldococcaceae; Methanocaldococcus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
PubMed=8688087 [NCBI, ExPASy, EBI, Israel, Japan]
Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G., Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R., Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R., Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L., Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R., Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D., Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P., Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii.";
Science 273:1058-1073(1996).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L77117; AAB98641.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A64381; A64381.
RefSeq NP_247633.1; -.
3D structure databases
ModBase Q58065.
Enzyme and pathway databases
BioCyc MJAN243232:MJ_0649-MON; -.
Family and domain databases
InterPro IPR000759; Adrndx_reductase.
IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR001100; Pyr_nuc-diS_OxRdtase.
IPR004099; Pyr_nucl-diS_OxRdtase_dimer.
IPR001327; Pyr_OxRdtase_NAD_bd.
Graphical view of domain structure.
Gene3D G3DSA:3.30.390.30; Pyr_redox_dim; 1.
Pfam PF00070; Pyr_redox; 2.
PF07992; Pyr_redox_2; 1.
PF02852; Pyr_redox_dim; 1.
Pfam graphical view of domain structure.
PRINTS PR00419; ADXRDTASE.
PR00368; FADPNR.
PR00411; PNDRDTASEI.
ProDom PD000139; FAD_pyr_redox; 1.
[Domain structure / List of seq. sharing at least 1 domain]
BLOCKS Q58065.
Genome annotation databases
GeneID 1451515; -.
GenomeReviews L77117_GR; MJ0649.
KEGG mja:MJ0649; -.
NMPDR fig|243232.1.peg.670; -.
TIGR MJ0649; -.
Phylogenomic databases
HOGENOM Q58065; -.
Other
ProtoNet Q58065.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; FAD; Flavoprotein; NAD; Oxidation; Oxidoreductase; Redox-active center.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   448  448     Putative NADH oxidase. PRO_0000184704
NP_BIND   7    11  5     FAD (By similarity). 
NP_BIND   110   113  4     FAD (By similarity). 
NP_BIND   152   167  16     NAD (By similarity). 
NP_BIND   271   281  11     FAD (By similarity). 
ACT_SITE   42    42        Redox-active. 
BINDING   42    42        FAD (By similarity). 
BINDING   132   132        FAD (By similarity). 
BINDING   243   243        NAD; via amide nitrogen (By similarity). 
MOD_RES   42    42        Cysteine sulfenic acid (-SOH) (By similarity). 
Sequence information
Length: 448 AA [This is the length of the unprocessed precursor] Molecular weight: 48876 Da [This is the MW of the unprocessed precursor] CRC64: 8790664DF98D9DCD [This is a checksum on the sequence]
        10         20         30         40         50         60 
MRAIIIGSGA AGLTTASTIR KYNKDMEIVV ITKEKEIAYS PCAIPYVIEG AIKSFDDIIM 

        70         80         90        100        110        120 
HTPEDYKRER NIDILTETTV IDVDSKNNKI KCVDKDGNEF EMNYDYLVLA TGAEPFIPPI 

       130        140        150        160        170        180 
EGKDLDGVFK VRTIEDGRAI LKYIEENGCK KVAVVGAGAI GLEMAYGLKC RGLDVLVVEM 

       190        200        210        220        230        240 
APQVLPRFLD PDMAEIVQKY LEKEGIKVML SKPLEKIVGK EKVEAVYVDG KLYDVDMVIM 

       250        260        270        280        290        300 
ATGVRPNIEL AKKAGCKIGK FAIEVNEKMQ TSIPNIYAVG DCVEVIDFIT GEKTLSPFGT 

       310        320        330        340        350        360 
AAVRQGKVAG KNIAGVEAKF YPVLNSAVSK IGDLEIGGTG LTAFSANLKR IPIVIGRAKA 

       370        380        390        400        410        420 
LTRARYYPGG KEIEIKMIFN EDGKVVGCQI VGGERVAERI DAMSIAIFKK VSAEELANME 

       430        440 
FCYAPPVSMV HEPLSLAAED ALKKLSNK 

Q58065 in FASTA format

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