[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=IAM 11059; PubMed=8535000 [NCBI, ExPASy, EBI, Israel, Japan] Yamada A., Dairi T., Ohno Y., Huang X., Asano Y.; "Nucleotide sequencing of phenylalanine dehydrogenase gene from Bacillus badius IAM 11059."; Biosci. Biotechnol. Biochem. 59:1994-1995(1995).

Comments

CATALYTIC ACTIVITY: L-phenylalanine + H₂O + NAD⁺ = phenylpyruvate + NH₃ + NADH.
PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis; L-phenylalanine from phenylpyruvate (PDH route): step 1/1 .
SIMILARITY: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

D50261; BAA08816.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

JC4328; JC4328.

3D structure databases

HSSP

Q59771; 1C1D. [HSSP ENTRY / PDB]

ModBase

Q59224.

Family and domain databases

InterPro

IPR006095; Glu/Leu/Phe/Val_DHase.
IPR006096; Glu/Leu/Phe/Val_DHase_C.
IPR006097; Glu/Leu/Phe/Val_DHase_dimer.
IPR016211; Glu/Phe/Leu/Val_DHase_bac/arc.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.

Pfam

PF00208; ELFV_dehydrog; 1.
PF02812; ELFV_dehydrog_N; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000188; Phe_leu_dh; 1.

PRINTS

PR00082; GLFDHDRGNASE.

PROSITE

PS00074; GLFV_DEHYDROGENASE; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 380`	`380`	`Phenylalanine dehydrogenase.`	`PRO_0000182806`
`NP_BIND`	`190 196`	`7`	`NAD (Potential).`

Sequence information

Length: 380 AA [This is the length of the unprocessed precursor]

Molecular weight: 41353 Da [This is the MW of the unprocessed precursor]

CRC64: ABB94657BA6A109A [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSLVEKTSII KDFTLFEKMS EHEQVVFCND PATGLRAIIA IHDTTLGPAL GGCRMQPYNS 

        70         80         90        100        110        120 
VEEALEDALR LSKGMTYKCA ASDVDFGGGK AVIIGDPQKD KSPELFRAFG QFVDSLGGRF 

       130        140        150        160        170        180 
YTGTDMGTNM EDFIHAMKET NCIVGVPEAY GGGGDSSIPT AMGVLYGIKA TNKMLFGKDD 

       190        200        210        220        230        240 
LGGVTYAIQG LGKVGYKVAE GLLEEGAHLF VTDINEQTLE AIQEKAKTTS GSVTVVASDE 

       250        260        270        280        290        300 
IYSQEADVFV PCAFGGVVND ETMKQFKVKA IAGSANNQLL TEDHGRHLAD KGILYAPDYI 

       310        320        330        340        350        360 
VNSGGLIQVA DELYEVNKER VLAKTKHIYD AILEVYQQAE LDQITTMEAA NRMCEQRMAA 

       370        380 
RGRRNSFFTS SVKPKWDIRN

Q59224 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools