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UniProtKB/Swiss-Prot entry Q5E7R0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name E4PD_VIBF1
Primary accession number Q5E7R0
Secondary accession numbers None
Integrated into Swiss-Prot on July 10, 2007
Sequence was last modified on March 15, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 25)
Name and origin of the protein
Protein name D-erythrose-4-phosphate dehydrogenase
Synonyms E4PDH
EC 1.2.1.72
Gene name
Name: epd
OrderedLocusNames: VF_0441
From
Vibrio fischeri (strain ATCC 700601 / ES114) [TaxID: 312309] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Aliivibrio.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0409900102; PubMed=15703294 [NCBI, ExPASy, EBI, Israel, Japan]
Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R., Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E., Stevens A., Visick K., Whistler C., Greenberg E.P.;
"Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with pathogenic congeners.";
Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000020; AAW84936.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_203824.1; -.
3D structure databases
ModBase Q5E7R0.
Enzyme and pathway databases
BioCyc VFIS312309:VF0441-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0048001; Molecular function: erythrose-4-phosphate dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0042823; Biological process: pyridoxal phosphate biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0008615; Biological process: pyridoxine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01640; -; 1.
PBIL [Tree]
InterPro IPR006422; E4P_DHase_bac.
IPR000173; GlycerAld_3-P_DHase.
Graphical view of domain structure.
PANTHER PTHR10836; GAP_DH; 1.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
PRINTS PR00078; G3PDHDRGNASE.
TIGRFAMs TIGR01532; E4PD_g-proteo; 1.
PROSITE PS00071; GAPDH; FALSE_NEG.
BLOCKS Q5E7R0.
Genome annotation databases
GeneID 3278161; -.
GenomeReviews CP000020_GR; VF_0441.
KEGG vfi:VF0441; -.
NMPDR fig|312309.3.peg.441; -.
Phylogenomic databases
HOGENOM Q5E7R0; -.
Genome annotation databases
CMR Q5E7R0; VF_0441.
Other
ProtoNet Q5E7R0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; NAD; Oxidoreductase; Pyridoxine biosynthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   339  339     D-erythrose-4-phosphate dehydrogenase. PRO_0000293174
NP_BIND   11    12  2     NAD (By similarity). 
REGION   158   160  3     Substrate binding (Potential). 
REGION   217   218  2     Substrate binding (Potential). 
ACT_SITE   159   159        Nucleophile (By similarity). 
BINDING   204   204        Substrate (Potential). 
BINDING   240   240        Substrate (Potential). 
BINDING   322   322        NAD (By similarity). 
SITE   186   186  1     Activates thiol group during catalysis (By similarity). 
Sequence information
Length: 339 AA [This is the length of the unprocessed precursor] Molecular weight: 37603 Da [This is the MW of the unprocessed precursor] CRC64: 1D03481B431CE114 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MLRVAINGFG RIGRSVLRAL YESDKRDKIE VVAVNELSQP EAMAHLFQYD STHGRFQHKV 

        70         80         90        100        110        120 
THDQEYPYSD VPDSSQDKVR ILHQADLSLL PWQSLEVDLV LDCTGVYGSK SDGEKHITAG 

       130        140        150        160        170        180 
AKKVLFSHPG GSDLDNTIIY GVNHDTLLPE HRIVSNGSCT TNCIIPVIKA IDDAFGIDSG 

       190        200        210        220        230        240 
TITTIHSSMN DQQVIDAYHS DLRRTRAASQ SIIPVDTKLH KGIERIFPKF SNKFEAISVR 

       250        260        270        280        290        300 
VPTVNVTAMD LSVTINTNVK VNDINQTIVN ASRCTLHNIV DYTEAPLVSI DFNHDPHSAI 

       310        320        330 
VDGSQTRVSN GHLVKMLVWC DNEWGFANRM LDTALAMSK
Q5E7R0 in FASTA format

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