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UniProtKB/Swiss-Prot entry Q5EBG2

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name T23O_XENTR
Primary accession number Q5EBG2
Secondary accession numbers None
Integrated into Swiss-Prot on July 25, 2006
Sequence was last modified on March 15, 2005 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 20)
Name and origin of the protein
Protein name Tryptophan 2,3-dioxygenase
Synonyms TO
EC 1.13.11.11
Tryptophan pyrrolase
Tryptophanase
Tryptophan oxygenase
Tryptamin 2,3-dioxygenase
TRPO
Gene name
Name: tdo2
From
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) [TaxID: 8364] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
NIH - Xenopus Gene Collection (XGC) project;
Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BC089667; AAH89667.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_001015733.1; -.
UniGene Str.37472
3D structure databases
ModBase Q5EBG2.
Family and domain databases
InterPro IPR004981; Trp_2_3_dOase.
Graphical view of domain structure.
PANTHER PTHR10138; Trp_2_3_dOase; 1.
Pfam PF03301; Trp_dioxygenase; 1.
Pfam graphical view of domain structure.
BLOCKS Q5EBG2.
Genome annotation databases
Ensembl ENSXETG00000022396; Xenopus tropicalis. [Contig view]
GeneID 548450; -.
KEGG xtr:548450; -.
Phylogenomic databases
HOVERGEN Q5EBG2; -.
Other
ProtoNet Q5EBG2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Dioxygenase; Heme; Iron; Metal-binding; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   406  406     Tryptophan 2,3-dioxygenase. PRO_0000247477
Sequence information
Length: 406 AA [This is the length of the unprocessed precursor] Molecular weight: 47700 Da [This is the MW of the unprocessed precursor] CRC64: EEF95FDF71884F8C [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSGCPFMGKK HHFNFSELSL EDKNEDSSQE GLNKASKGGL IYGDYLQLDK VLNAQELQSE 

        70         80         90        100        110        120 
KKGNKIHDEH LFIVTHQAYE LWFKQILWEL DSVREIFQNG HVRDERNMLK VVTRIHRISM 

       130        140        150        160        170        180 
ILKLLVEQFS VLETMTAMDF FDFRDYLSPA SGFQSLQFRL LENKIGVPEI LRVPYNRRHY 

       190        200        210        220        230        240 
RDNFKGETNE LLLKSEQELT LLGLVEAWLE RTPGLEEEGF HFWGKLEANI FRGLEEELQT 

       250        260        270        280        290        300 
VKTKPDSEEK EEQLAELQKQ KELFGALFDE RRHEHLLSKG ERRLSYKALK GALMIYFYRE 

       310        320        330        340        350        360 
EPRFQVPFQL LTSLMDIDTL MTKWRYNHVC MVHRMIGSKA GTGGSSGYQY LRSTVSDRYK 

       370        380        390        400 
VFVDLFNLST YLVPRHWVPR LNPSIHKFLY TAECCDSSYF SSDDSD
Q5EBG2 in FASTA format

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