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UniProtKB/Swiss-Prot entry Q5FB27

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ADO_MACFA
Primary accession number Q5FB27
Secondary accession numbers None
Integrated into Swiss-Prot on April 12, 2005
Sequence was last modified on March 15, 2005 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 24)
Name and origin of the protein
Protein name Aldehyde oxidase
Synonym EC 1.2.3.1
Gene name
Name: AOX1
From
Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey) [TaxID: 9541] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Liver;
Hoshino K.;
"Molecular cloning and characterization of monkey aldehyde oxidase.";
Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AB201545; BAD89382.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
ModBase Q5FB27.
Family and domain databases
InterPro IPR002888; 2Fe-2S_bd.
IPR006058; 2Fe2S_fd_BS.
IPR000674; Ald_Oxase/Xan_DHase_a/b.
IPR016208; Ald_Oxase/xanthine_DHase.
IPR014313; Aldehyde_oxidase.
IPR008274; AldOxase/xan_DHase_Mopterin-bd.
IPR012675; b-grasp_ferredoxin-like.
IPR005107; CO_DHase_flav_C.
IPR016169; CO_DHase_flavot_FAD-bd_sub2.
IPR016167; FAD-bd_2_sub1.
IPR001041; Ferredoxin.
IPR002346; Mopterin_DHase_FAD-bd.
IPR000572; OxRdtase_Mopterin-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.30.365.10; Ald_xan_DH_mo_bd; 2.
G3DSA:3.90.1170.50; Aldxan_DH_hamm; 1.
G3DSA:3.30.390.50; CO_DH_flav_C; 1.
G3DSA:3.30.465.10; CO_DH_flavoprot_FAD-bd_sub2; 1.
G3DSA:3.30.43.10; FAD-binding_2_sub1; 1.
G3DSA:3.10.20.30; Ferredoxin_fold; 1.
Pfam PF01315; Ald_Xan_dh_C; 1.
PF02738; Ald_Xan_dh_C2; 1.
PF03450; CO_deh_flav_C; 1.
PF00941; FAD_binding_5; 1.
PF00111; Fer2; 1.
PF01799; Fer2_2; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000127; Xanthine_DH; 1.
ProDom PD186071; 2Fe-2S_bind; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR02969; mam_aldehyde_ox; 1.
PROSITE PS00197; 2FE2S_FER_1; 1.
PS51085; 2FE2S_FER_2; 1.
PS51387; FAD_PCMH; 1.
PS00559; MOLYBDOPTERIN_EUK; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q5FB27.
Phylogenomic databases
HOVERGEN Q5FB27; -.
Other
ProtoNet Q5FB27.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
2Fe-2S; Cytoplasm; FAD; Flavoprotein; Iron; Iron-sulfur; Metal-binding; Molybdenum; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   1338  1338     Aldehyde oxidase. PRO_0000166105
DOMAIN   5     92  88     2Fe-2S ferredoxin-type. 
DOMAIN   236    421  186     FAD-binding PCMH-type. 
METAL   44     44        Iron-sulfur (2Fe-2S) (By similarity). 
METAL   49     49        Iron-sulfur (2Fe-2S) (By similarity). 
METAL   52     52        Iron-sulfur (2Fe-2S) (By similarity). 
Sequence information
Length: 1338 AA [This is the length of the unprocessed precursor] Molecular weight: 147713 Da [This is the MW of the unprocessed precursor] CRC64: 0A3F07058DCADAD6 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MDRASELLFY VNGRKVIEKN VDPETMLLPY LRKKLRLTGT KYGCGGGGCG ACTVMISRYN 

        70         80         90        100        110        120 
PITNRIRHHP ANACLIPICS LYGTAVTTVE GIGSTHTRIH PVQERIAKCH GTQCGFCTPG 

       130        140        150        160        170        180 
MVMSIYTLLR NHPEPTLDQL TDALGGNLCR CTGYRPIIDA CKTFCETSGC CQSKENGVCC 

       190        200        210        220        230        240 
LDQGINGLPE FEEGSKTSPK LFAEEEFLPL DPTQELIFPP ELMIMAEKQP QRTRVFGSER 

       250        260        270        280        290        300 
MMWFSPVTLK ELLEFKFKYP QAPVIMGNTS VGPQVKFKGV FHPGYNSPDR IEEPECCKPY 

       310        320        330        340        350        360 
TYGLTLGAGL SLAQVKDILA DVVQKLPEEK TQTYHALLKH LGTLAGSQIR NMASLGGHII 

       370        380        390        400        410        420 
SRHPDSDLNP ILAVGNCTLN LLSKEGKRQI PLNEQFLSKC PNADLKPQEI LVSVNIPYSR 

       430        440        450        460        470        480 
KLEFVSAFRQ AQRQENALAI VNSGMRVFFG EGHGIIRELS ISYGGVGPAT ICAKNSCQKL 

       490        500        510        520        530        540 
IGRHWNEEML DTACRLVLEE VSLSGSAPGG KVEFKRTLII SFLFKFYLEV SQILKKMDPI 

       550        560        570        580        590        600 
HYPSLADKYE SALEDLHSKH HCSTLKYQHM GPKQHPEDPI GHPIMHLSGV KHATGEAIYC 

       610        620        630        640        650        660 
DDMPPVDQEL FLTFVTSSRA HAKIVSIDLS EALSMPGVVD VITAEHLSDV NSFCFFTEAE 

       670        680        690        700        710        720 
EFLATDKVFC VGQLVCAVLA DSEVQAKRAA KQVKIVYQDL EPLILTIKEA IQHNSFFEPE 

       730        740        750        760        770        780 
RKLEYGNVDE AFKVVDQILE GEIHMGGQEH FYMETQSMLV VPKGEDQEMD VYVSTQFPKY 

       790        800        810        820        830        840 
IQDIVASTLK LPANKVMCHV KRVGGAFGGK AFKTGVIAAV TAFAANKHGR AVRCVLERGE 

       850        860        870        880        890        900 
DMLITGGRHP YLGKYKAGFM NDGRILALDM EHYSNAGNSL DESLLVIEMG LLKMDNAYKF 

       910        920        930        940        950        960 
PNLRCRGWAC RTNLPSNTAF RGFGFPQAGL ITESCIMEVA AKCGLSPEKV RMINMYKEID 

       970        980        990       1000       1010       1020 
QTPYKQEINA KNLIQCWREC MAVSSYSLRK AAVEKFNAEN YWKKKGLAMV PLKYPVGLGS 

      1030       1040       1050       1060       1070       1080 
RAAGQAAALV HIYLDGSVLV THGGIEMGQG VHTKMIQVVS RELGMPISNV HLRGTSTETV 

      1090       1100       1110       1120       1130       1140 
PNANVSGGSV VADLNGLAVK DACQILLKRL EPIISKNPKG TWKDWAQTAF DESISLSAIG 

      1150       1160       1170       1180       1190       1200 
YFRGYESDIN WEKGEGHPFE YFVYGAACSE VEIDCLTGDH KNIRTDIVMD VGCSINPAID 

      1210       1220       1230       1240       1250       1260 
IGQIEGAFIQ GMGLYTIEEL NYSPQGVLHT RGPDQYKIPA ICDTPTEFHI SLLPPSENSN 

      1270       1280       1290       1300       1310       1320 
TLYSSKGLGE SGVFLGCSVF FAIHDAVSAA RRERGLHGPL TLNSPLTPEK IRMACEDKFT 

      1330 
KMIPRDEPGS CVPWNVPV
Q5FB27 in FASTA format

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