NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1007/s00203-004-0742-9; PubMed=15551059 [NCBI, ExPASy, EBI, Israel, Japan]
Rabus R., Kube M., Heider J., Beck A., Heitmann K., Widdel F., Reinhardt R.;
"The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1.";
Arch. Microbiol. 183:27-36(2005).

Comments

CATALYTIC ACTIVITY: 2,3,4,5-tetrahydrodipicolinate + NAD(P)⁺ = 2,3-dihydrodipicolinate + NAD(P)H.
PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; tetrahydrodipicolinate from L-aspartate: step 4/4 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the dihydrodipicolinate reductase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CR555306; CAI08848.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_159749.1; -.

3D structure databases

ModBase

Q5P1G6.

Enzyme and pathway databases

BioCyc

ASP76114:EBA4812-MON; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0008839;	Molecular function: dihydrodipicolinate reductase activity (inferred from electronic annotation from HAMAP).
GO:0019877;	Biological process: diaminopimelate biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00102; -; 1.
PBIL [Tree]

InterPro

IPR000846; DapB.
IPR011770; DapB_bac/pln.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 2.

PANTHER

PTHR20836; DapB_bac/pln; 1.

Pfam

PF05173; DapB_C; 1.
PF01113; DapB_N; 1.
Pfam graphical view of domain structure.

ProDom

PD004105; DapB; 1.
[Domain structure / List of seq. sharing at least 1 domain]

TIGR00036; dapB; 1.

PS01298; DAPB; 1.

Genome annotation databases

GeneID

3180017; -.

GenomeReviews

CR555306_GR; AZOSEA27230.

KEGG

eba:ebA4812; -.

NMPDR

fig|76114.4.peg.2620; -.

Phylogenomic databases

HOGENOM

Q5P1G6; -.

Genome annotation databases

CMR

Q5P1G6; AZOSEA27230.

Other

ProtoNet

Q5P1G6.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Amino-acid biosynthesis; Complete proteome; Cytoplasm; Diaminopimelate biosynthesis; Lysine biosynthesis; NADP; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 276`	`276`		`Dihydrodipicolinate reductase.`	`PRO_0000228320`

Sequence information

Length: 276 AA [This is the length of the unprocessed precursor]

Molecular weight: 28962 Da [This is the MW of the unprocessed precursor]

CRC64: F2138D20D2FFF1B4 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSSKRNSLML PLRIAIAGAS GRMGRMLIEA TLKEEGAVLA SAFDRPGTTF IGRDAGELSG 

        70         80         90        100        110        120 
SATGILITDD PRAAIAAADC VIDFTRPEGT LAHLALAREL GKAMVIGTTG FSTAEKEAIA 

       130        140        150        160        170        180 
AAAQAIPIVF APNMAVGVNA VFKLLEVAAR ILDDGYDVEV IEAHHRFKVD APSGTALRMG 

       190        200        210        220        230        240 
EVVACELGRD LETCAIYGRE GVTGERKAET IGFSTIRGGD VVGDHTVLFA GIGERIEITH 

       250        260        270 
RSGSRMPYAS GSLRAARFLA GRSSGLFDMQ DVLGLR

Q5P1G6 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools