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UniProtKB/Swiss-Prot entry Q5RBD5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name IVD_PONAB
Primary accession number Q5RBD5
Secondary accession numbers None
Integrated into Swiss-Prot on July 5, 2005
Sequence was last modified on December 21, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 29)
Name and origin of the protein
Protein name Isovaleryl-CoA dehydrogenase, mitochondrial [Precursor]
Synonyms IVD
EC 1.3.99.10
Gene name
Name: IVD
From
Pongo abelii (Sumatran orangutan) [TaxID: 9601] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Kidney;
The German cDNA consortium;
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR858716; CAH90925.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
SMR Q5RBD5; 35-421.
ModBase Q5RBD5.
Ontologies
GO
GO:0005759; Cellular component: mitochondrial matrix (inferred from electronic annotation from UniProtKB-SubCell).
GO:0008470; Molecular function: isovaleryl-CoA dehydrogenase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR006091; Acyl-CoA_DHase/Oxase_M.
IPR006089; Acyl-CoA_DHase_CS.
IPR006092; Acyl-CoA_DHase_N.
IPR006090; Acyl-CoA_Oxase/DHase_1.
IPR013786; AcylCoA_DH/ox_N.
IPR013764; AcylCoA_oxidase/DH_1/2_C.
Graphical view of domain structure.
Gene3D G3DSA:2.40.110.10; Acyl_CoA_DH/ox_M; 1.
G3DSA:1.10.540.10; AcylCoA_DH/ox_N; 1.
G3DSA:1.20.140.10; AcylCoA_DH_1/2_C; 1.
Pfam PF00441; Acyl-CoA_dh_1; 1.
PF02770; Acyl-CoA_dh_M; 1.
PF02771; Acyl-CoA_dh_N; 1.
Pfam graphical view of domain structure.
PROSITE PS00072; ACYL_COA_DH_1; 1.
PS00073; ACYL_COA_DH_2; 1.
BLOCKS Q5RBD5.
Phylogenomic databases
HOVERGEN Q5RBD5; -.
Other
ProtoNet Q5RBD5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Acetylation; FAD; Flavoprotein; Mitochondrion; Oxidoreductase; Transit peptide.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1    29  29     Mitochondrion (By similarity). 
CHAIN   30   423  394     Isovaleryl-CoA dehydrogenase, mitochondrial. PRO_0000000533
ACT_SITE   283   283        Proton acceptor (By similarity). 
MOD_RES   75    75        N6-acetyllysine (By similarity). 
Sequence information
Length: 423 AA [This is the length of the unprocessed precursor] Molecular weight: 46275 Da [This is the MW of the unprocessed precursor] CRC64: 87A4DB40CF56D886 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MATATRLLGW RVASWRMRPP PAGFVSQRAH SLLPVDDAIN GLSEEQRQLR QTVAKFLQEH 

        70         80         90        100        110        120 
LAPKAQEIDR SNEFKNLREF WKQLGNLGVL GITAPVQYGG SGLGYLEHVL VMEEISRASG 

       130        140        150        160        170        180 
AVGLSYGAHS NLCINQLVRN GNEAQKEKYL PKLISGEYIG ALAMSEPNAG SDVVSMKLKA 

       190        200        210        220        230        240 
EKKGNHYILN GNKFWITNGP DADVLIVYAK TDLAAVPASR GITAFIVEKG MPGFSTSKKL 

       250        260        270        280        290        300 
DKLGMRGSNT CELIFEDCKV PAANILGHEN KGVYVLMSGL DLERLVLAGG PLGLMQAVLD 

       310        320        330        340        350        360 
HTIPYLHVRE AFGQKIGHFQ LMQGKMADMY TRLMACRQYV YNVAKACDEG HCTAKDCAGV 

       370        380        390        400        410        420 
ILYSAECATQ VALDGIQCFG GNGYINDFPM GRFLRDAKLY EIGAGTSEVR RLVIGRAFNA 


DFH
Q5RBD5 in FASTA format

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