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UniProtKB/Swiss-Prot entry Q5RCH8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PECR_PONAB
Primary accession number Q5RCH8
Secondary accession numbers None
Integrated into Swiss-Prot on March 29, 2005
Sequence was last modified on December 21, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 21)
Name and origin of the protein
Protein name Peroxisomal trans-2-enoyl-CoA reductase
Synonym EC 1.3.1.38
Gene name
Name: PECR
From
Pongo abelii (Sumatran orangutan) [TaxID: 9601] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Kidney;
The German cDNA consortium;
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR858292; CAH90529.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
SMR Q5RCH8; 7-303.
ModBase Q5RCH8.
Ontologies
GO
GO:0019166; Molecular function: trans-2-enoyl-CoA reductase (NADPH) activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR002198; DHase_sc/Rdtase_SDR.
IPR002347; Glc/ribitol_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR19410; ADH_short_C2; 1.
Pfam PF00106; adh_short; 1.
Pfam graphical view of domain structure.
PRINTS PR00081; GDHRDH.
PR00080; SDRFAMILY.
PROSITE PS00061; ADH_SHORT; FALSE_NEG.
BLOCKS Q5RCH8.
Phylogenomic databases
HOVERGEN Q5RCH8; -.
Other
ProtoNet Q5RCH8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Fatty acid biosynthesis; Lipid synthesis; NADP; Oxidoreductase; Peroxisome.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   303  303     Peroxisomal trans-2-enoyl-CoA reductase. PRO_0000054742
NP_BIND   23    47  25     NADP (By similarity). 
MOTIF   301   303  3     Microbody targeting signal (By similarity). 
ACT_SITE   179   179        Proton acceptor (By similarity). 
Sequence information
Length: 303 AA [This is the length of the unprocessed precursor] Molecular weight: 32589 Da [This is the MW of the unprocessed precursor] CRC64: 7B152CFB5C10A1E1 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MASWAKGRSY LAPGLLQGQV AIVTGGATGI GKAIVKELLE LGSNVVIASR KLERLKSAAG 

        70         80         90        100        110        120 
ELQANLPPTK QARVIPIQCN IRNEEEVNNL VKSTLDIFGK INFLVNNGGG QFLSLAEHIS 

       130        140        150        160        170        180 
SKGWHAVLET NLTGTFYMCK AVYSSWMKEH GGSIVNIIVS IKTGLPLAVH SGAARAGVYN 

       190        200        210        220        230        240 
LTKSLALEWA CSGVRINCVA PGVIYSQTAV ENYGSYGQSF FEESFQKIPA KRIGVPEEVS 

       250        260        270        280        290        300 
SVVCFLLSPA ASFITGQSVD VDGGRSLYTH SYEIPDHDNW PKGAGDLSVV KRMKETFKEK 


AKL 

Q5RCH8 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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