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UniProtKB/Swiss-Prot entry Q5V3R2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DYR1_HALMA
Primary accession number Q5V3R2
Secondary accession numbers None
Integrated into Swiss-Prot on June 21, 2005
Sequence was last modified on December 7, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 30)
Name and origin of the protein
Protein name Dihydrofolate reductase 1
Synonym EC 1.5.1.3
Gene name
Name: folA1
OrderedLocusNames: rrnAC0859
From
Haloarcula marismortui (Halobacterium marismortui) [TaxID: 2238] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Haloarcula.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 43049 / DSM 3752 / JCM 8966;
DOI=10.1101/gr.2700304; PubMed=15520287 [NCBI, ExPASy, EBI, Israel, Japan]
Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W., Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E., Hood L., Ng W.V.;
"Genome sequence of Haloarcula marismortui: a halophilic archaeon from the Dead Sea.";
Genome Res. 14:2221-2234(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AY596297; AAV45840.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_135546.1; -.
3D structure databases
ModBase Q5V3R2.
Enzyme and pathway databases
BioCyc HMAR272569:RRNAC0859-MON; -.
Family and domain databases
InterPro IPR012259; DHFR.
IPR001796; DHFR_reg.
Graphical view of domain structure.
PANTHER PTHR11549:SF1; DHFR; 1.
Pfam PF00186; DHFR_1; 1.
Pfam graphical view of domain structure.
PRINTS PR00070; DHFR.
PROSITE PS00075; DHFR_1; 1.
PS51330; DHFR_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q5V3R2.
Genome annotation databases
GeneID 3130204; -.
GenomeReviews AY596297_GR; rrnAC0859.
KEGG hma:rrnAC0859; -.
NMPDR fig|272569.1.peg.810; -.
Phylogenomic databases
HOGENOM Q5V3R2; -.
Genome annotation databases
CMR Q5V3R2; rrnAC0859.
Other
ProtoNet Q5V3R2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; One-carbon metabolism; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom To Length Description FTId
CHAIN   1   185  185     Dihydrofolate reductase 1. PRO_0000186431
DOMAIN   8   185  178     DHFR. 
Sequence information
Length: 185 AA [This is the length of the unprocessed precursor] Molecular weight: 20284 Da [This is the MW of the unprocessed precursor] CRC64: 943E45089F069380 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTMIPDTELV LVVAADENNV IGLDGGVPWH YPEDVRQYKN RIAGHPIILG RRTFESMKPI 

        70         80         90        100        110        120 
PDCYTVVLTS DDRRSADSET VEYATTPQIA VEAAARAGAS GAFAGDSAGA DSSPPVTYVI 

       130        140        150        160        170        180 
GGEAVYDLFL PFAGRVFLSR IHEHNEGDRY FPDLGAEWTE LSREPHDGFD VIEYEQASPR 


PLDDL 

Q5V3R2 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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