NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/ng1447; PubMed=15467720 [NCBI, ExPASy, EBI, Israel, Japan]
Cazalet C., Rusniok C., Brueggemann H., Zidane N., Magnier A., Ma L., Tichit M., Jarraud S., Bouchier C., Vandenesch F., Kunst F., Etienne J., Glaser P., Buchrieser C.;
"Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity.";
Nat. Genet. 36:1165-1173(2004).

Comments

CATALYTIC ACTIVITY: Coproporphyrinogen-III + O₂ + 2 H⁺ = protoporphyrinogen-IX + 2 CO₂ + 2 H₂O.
PATHWAY: Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen III (O2 route): step 1/1 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the aerobic coproporphyrinogen III oxidase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CR628336; CAH12374.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_123547.1; -.

3D structure databases

ModBase

Q5X5U7.

Enzyme and pathway databases

BioCyc

LPNE297246:LPP1223-MON; -.

Organism-specific databases

LegioList

lpp1223; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004109;	Molecular function: coproporphyrinogen oxidase activity (inferred from electronic annotation from HAMAP).
GO:0006779;	Biological process: porphyrin biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00333; -; 1.
PBIL [Tree]

InterPro

IPR001260; Coprogen_oxidas.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.1500.10; Coprogen_oxidas; 1.

PANTHER

PTHR10755; Coprogen_oxidas; 1.

Pfam

PF01218; Coprogen_oxidas; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000166; Coproporphyri_ox; 1.

PRINTS

PR00073; COPRGNOXDASE.

PROSITE

PS01021; COPROGEN_OXIDASE; 1.

BLOCKS

Q5X5U7.

Genome annotation databases

GeneID

3117830; -.

GenomeReviews

CR628336_GR; lpp1223.

KEGG

lpp:lpp1223; -.

Phylogenomic databases

HOGENOM

Q5X5U7; -.

Genome annotation databases

CMR

Q5X5U7; lpp1223.

Other

ProtoNet

Q5X5U7.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Oxidoreductase; Porphyrin biosynthesis.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 311`	`311`		`Coproporphyrinogen 3 oxidase, aerobic.`	`PRO_0000109900`

Sequence information

Length: 311 AA [This is the length of the unprocessed precursor]

Molecular weight: 35882 Da [This is the MW of the unprocessed precursor]

CRC64: 6DF53E59C0EB4669 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSISKTLPYN AIEQIKSYLL QLQNTICVLL ESIDGKTRFH EDSWQRAAGG GGRTRIMTNG 

        70         80         90        100        110        120 
NVFEKAGVNF SHVSGEQLPA SASAHREELA GRHFSALGVS LVIHPQNPYV PTTHANVRFF 

       130        140        150        160        170        180 
VAEKEDSEPV WWFGGGFDLT PYYGFVEDCE HWHQTALNAC LPFGETIYPK FKRWCDDYFF 

       190        200        210        220        230        240 
IKHRNEARGI GGLFFDDYNE ISFDHSFELM RSIGDHFILA YEPIVARRKD IPFGNREKAF 

       250        260        270        280        290        300 
QNYRRGRYAE FNLVYDRGTL FGLQSGGRTE SILMSLPPTV HWEYNWHPEK GSDEEKLYTD 

       310 
FLPAKDWLKK E

Q5X5U7 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools