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UniProtKB/Swiss-Prot entry Q5X9A8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name UDG_STRP6
Primary accession number Q5X9A8
Secondary accession numbers None
Integrated into Swiss-Prot on August 30, 2005
Sequence was last modified on November 23, 2004 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 27)
Name and origin of the protein
Protein name UDP-glucose 6-dehydrogenase
Synonyms UDP-Glc dehydrogenase
UDP-GlcDH
UDPGDH
EC 1.1.1.22
Gene name
Name: hasB
OrderedLocusNames: M6_Spy1870
From
Streptococcus pyogenes serotype M6 [TaxID: 301450] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-946 / MGAS10394 / Serotype M6;
DOI=10.1086/422697; PubMed=15272401 [NCBI, ExPASy, EBI, Israel, Japan]
Banks D.J., Porcella S.F., Barbian K.D., Beres S.B., Philips L.E., Voyich J.M., DeLeo F.R., Martin J.M., Somerville G.A., Musser J.M.;
"Progress toward characterization of the group A Streptococcus metagenome: complete genome sequence of a macrolide-resistant serotype M6 strain.";
J. Infect. Dis. 190:727-738(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000003; AAT88005.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_061188.1; -.
3D structure databases
SMR Q5X9A8; 1-402.
ModBase Q5X9A8.
Enzyme and pathway databases
BioCyc SPYO286636:M6_SPY1870-MON; -.
Family and domain databases
InterPro IPR016040; NAD(P)-bd.
IPR017476; Nucleotide_sugar_DH.
IPR014027; UDP-Glc/GDP-Man_DHase_C.
IPR014026; UDP-Glc/GDP-Man_DHase_dimer.
IPR014028; UDP-Glc/GDP-Man_DHase_dimer-bd.
IPR001732; UDP-Glc/GDP-Man_DHase_N.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:3.40.50.1870; UDP-Glc/GDP-Man_DH_C; 1.
PANTHER PTHR11374; UDPG_MGDP_DH_Creg; 1.
Pfam PF00984; UDPG_MGDP_dh; 1.
PF03720; UDPG_MGDP_dh_C; 1.
PF03721; UDPG_MGDP_dh_N; 1.
Pfam graphical view of domain structure.
BLOCKS Q5X9A8.
Genome annotation databases
GeneID 2940772; -.
GenomeReviews CP000003_GR; M6_Spy1870.
KEGG spa:M6_Spy1870; -.
Phylogenomic databases
HOGENOM Q5X9A8; -.
Genome annotation databases
CMR Q5X9A8; M6_Spy1870.
Other
ProtoNet Q5X9A8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Capsule biogenesis/degradation; Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   402  402     UDP-glucose 6-dehydrogenase. PRO_0000074057
NP_BIND   2    19  18     NAD (Potential). 
ACT_SITE   260   260        By similarity. 
Sequence information
Length: 402 AA [This is the length of the unprocessed precursor] Molecular weight: 45483 Da [This is the MW of the unprocessed precursor] CRC64: DD1869D659F4CA58 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKIAVAGSGY VGLSLGVLLS LQNEVTIVDI LPSKVDKINN GLSPIQDEYI EYYLKSKQLS 

        70         80         90        100        110        120 
IKATLDSKAA YKEAELVIIA TPTNYNSRIN YFDTQHVETV IKEVLSVNSH ATLIIKSTIP 

       130        140        150        160        170        180 
IGFITEMRQK FQTDRIIFSP EFLRESKALY DNLYPSRIIV SCEENDSPKV KADAEKFALL 

       190        200        210        220        230        240 
LKSAAKKNNV PVLIMGASEA EAVKLFANTY LALRVAYFNE LDTYAESRKL NSHMIIQGIS 

       250        260        270        280        290        300 
YDDRIGMHYN NPSFGYGGYC LPKDTKQLLA NYNNIPQTLI EAIVSSNNVR KSYIAKQIIN 

       310        320        330        340        350        360 
VLKEQESPVK VVGVYRLIMK SNSDNFRESA IKDVIDILKS KDIKIIIYEP MLNKLESEDQ 

       370        380        390        400 
SVLVNDLENF KKQANIIVTN RYDNELQDVK NKVYSRDIFG RD 

Q5X9A8 in FASTA format

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