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UniProtKB/Swiss-Prot entry Q5ZUT5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ASTD_LEGPH
Primary accession number Q5ZUT5
Secondary accession numbers None
Integrated into Swiss-Prot on November 28, 2006
Sequence was last modified on November 23, 2004 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 29)
Name and origin of the protein
Protein name N-succinylglutamate 5-semialdehyde dehydrogenase
Synonyms EC 1.2.1.71
Succinylglutamic semialdehyde dehydrogenase
SGSD
Gene name
Name: astD
OrderedLocusNames: lpg1707
From
Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) [TaxID: 272624] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Legionellaceae; Legionella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1099776; PubMed=15448271 [NCBI, ExPASy, EBI, Israel, Japan]
Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G., Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V., Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S., Georghiou A., Chou I.-C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A., Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A., Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A., Russo J.J.;
"The genomic sequence of the accidental pathogen Legionella pneumophila.";
Science 305:1966-1968(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE017354; AAU27787.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_095734.1; -.
3D structure databases
ModBase Q5ZUT5.
Enzyme and pathway databases
BioCyc LPNE272624:LPG1707-MON; -.
Ontologies
GO
GO:0019544; Biological process: arginine catabolic process to glutamate (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01174; -; 1.
PBIL [Tree]
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR017649; SuccinylGlu_semiald_DH_AstD.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; FALSE_NEG.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
BLOCKS Q5ZUT5.
Genome annotation databases
GeneID 3077778; -.
GenomeReviews AE017354_GR; lpg1707.
KEGG lpn:lpg1707; -.
NMPDR fig|272624.3.peg.537; -.
Phylogenomic databases
HOGENOM Q5ZUT5; -.
Genome annotation databases
CMR Q5ZUT5; lpg1707.
Other
ProtoNet Q5ZUT5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Arginine metabolism; Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   496  496     N-succinylglutamate 5-semialdehyde dehydrogenase. PRO_0000262407
NP_BIND   229   234  6     NAD (By similarity). 
ACT_SITE   252   252        By similarity. 
ACT_SITE   286   286        By similarity. 
Sequence information
Length: 496 AA [This is the length of the unprocessed precursor] Molecular weight: 54696 Da [This is the MW of the unprocessed precursor] CRC64: C1704C21B77D38E6 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MMSKLQIIQS KGQYINGEWI KGNGLILEST NPASGTLLWQ GNNATDEEIA NACYVAHRAL 

        70         80         90        100        110        120 
KSWANTSFEE RARYTKAFVE QVEKNREQLA RLISLETGKP LWESQTEVSS VIGKVNLSIQ 

       130        140        150        160        170        180 
AYQERTWPKQ TETAEANACL RFKPHGIVVV LGAFNFPAHL SNGHIVPALL AGNTVLYKPS 

       190        200        210        220        230        240 
EHTPAVAELI IQCWHDSGLP PGVINCLQGN ANCGNTLLSQ DIQGVYFTGS YATGLRIHQQ 

       250        260        270        280        290        300 
FCNRPEVILA LEMGGNNPLV IDEVKDIDAA VYHTILSTMI TAGQRCTCAR RIIIPDSQTG 

       310        320        330        340        350        360 
DLFLERFAKA CKLMRIGSFD SQPEPFIGPV ISHVQALKHL HAQKQLIEMG GEIILPMSLL 

       370        380        390        400        410        420 
LEYTGLVSPG IIDMTRAKNP PDEEIFAPFA QIYRYNHFDE AIQLANQTRY GLSAGLLSDN 

       430        440        450        460        470        480 
KDHYQQFYQN IRAGLINWNR PTTGAASSLP FGGVGCSGNH RPSAYFAADY CAYPVASMEQ 

       490 
PLLTTPVQRL PGLVLE 

Q5ZUT5 in FASTA format

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