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UniProtKB/Swiss-Prot entry Q630E8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GUAC_BACCZ
Primary accession number Q630E8
Secondary accession numbers None
Integrated into Swiss-Prot on January 4, 2005
Sequence was last modified on October 25, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 31)
Name and origin of the protein
Protein name GMP reductase
Synonyms EC 1.7.1.7
Guanosine 5'-monophosphate oxidoreductase
Guanosine monophosphate reductase
Gene name
Name: guaC
OrderedLocusNames: BCE33L5151
From
Bacillus cereus (strain ZK / E33L) [TaxID: 288681] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.188.9.3382-3390.2006; PubMed=16621833 [NCBI, ExPASy, EBI, Israel, Japan]
Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C., Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A., Hill K.K., Hitchcock P., Jackson P.J., Keim P., Kewalramani A.R., Longmire J., Lucas S., Malfatti S., McMurry K., Meincke L.J., Misra M., Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B., Reilly L.P., Richardson P., Robinson D.L., Rubin E., Saunders E., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L., Brettin T.S., Gilna P.;
"Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis.";
J. Bacteriol. 188:3382-3390(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000001; AAU20281.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_086719.1; -.
3D structure databases
SMR Q630E8; 1-321.
ModBase Q630E8.
Enzyme and pathway databases
BioCyc BCER288681:BCE33L5151-MON; -.
Ontologies
GO
GO:0003920; Molecular function: GMP reductase activity (inferred from electronic annotation from HAMAP).
GO:0006163; Biological process: purine nucleotide metabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01511; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR005994; GMP_reduct2.
IPR015875; IMP_DH/GMP_Rdtase_CS.
IPR001093; IMP_DHase_GMPRtase.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF00478; IMPDH; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036500; GMP_red_Firmic; 1.
TIGRFAMs TIGR01306; GMP_reduct_2; 1.
PROSITE PS00487; IMP_DH_GMP_RED; 1.
BLOCKS Q630E8.
Genome annotation databases
GeneID 3022126; -.
GenomeReviews CP000001_GR; BCE33L5151.
KEGG bcz:BCZK5151; -.
Phylogenomic databases
HOGENOM Q630E8; -.
Genome annotation databases
CMR Q630E8; BCE33L5151.
Other
ProtoNet Q630E8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   327  327     GMP reductase. PRO_0000093749
NP_BIND   204   227  24     NADP (Potential). 
ACT_SITE   175   175        Thioimidate intermediate (By similarity). 
Sequence information
Length: 327 AA [This is the length of the unprocessed precursor] Molecular weight: 36148 Da [This is the MW of the unprocessed precursor] CRC64: 02AD48048B6224AE [This is a checksum on the sequence]
        10         20         30         40         50         60 
MENVFDYEDI QLIPAKCIVN SRSECDTTVT LGKHKFKLPV VPANMQTIID ERIATYLAEN 

        70         80         90        100        110        120 
NYFYIMHRFQ PEKRISFIRD MQSRGLIASI SVGVKEDEYE FVQQLAAEHL TPEYITIDIA 

       130        140        150        160        170        180 
HGHSNAVINM IQHIKKHLPE SFVIAGNVGT PEAVRELENA GADATKVGIG PGKVCITKIK 

       190        200        210        220        230        240 
TGFGTGGWQL AALRWCAKAA SKPIIADGGI RTNGDVAKSI RFGATMVMIG SLFAGHEESP 

       250        260        270        280        290        300 
GETIEKDGKL YKEYFGSASE FQKGEKKNVE GKKMFVEHKG SLEDTLIEME QDLQSSISYA 

       310        320 
GGTKLDSIRT VDYVVVKNSI FNGDKVY 

Q630E8 in FASTA format

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