ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q66ED3

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name CYSI_YERPS
Primary accession number Q66ED3
Secondary accession numbers None
Integrated into Swiss-Prot on September 13, 2005
Sequence was last modified on October 11, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 27)
Name and origin of the protein
Protein name Sulfite reductase [NADPH] hemoprotein beta-component
Synonyms SIR-HP
SIRHP
EC 1.8.1.2
Gene name
Name: cysI
OrderedLocusNames: YPTB0760
From
Yersinia pseudotuberculosis [TaxID: 633] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Yersinia.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=IP32953 / Serotype I;
DOI=10.1073/pnas.0404012101; PubMed=15358858 [NCBI, ExPASy, EBI, Israel, Japan]
Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O., Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L., Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C., Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M., Derbise A., Hauser L.J., Garcia E.;
"Insights into the evolution of Yersinia pestis through whole-genome comparison with Yersinia pseudotuberculosis.";
Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX936398; CAH20000.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_069301.1; -.
3D structure databases
SMR Q66ED3; 81-571.
ModBase Q66ED3.
Enzyme and pathway databases
BioCyc YPSE273123:YPTB0760-MON; -.
Ontologies
GO
GO:0004783; Molecular function: sulfite reductase (NADPH) activity (inferred from electronic annotation from HAMAP).
GO:0000103; Biological process: sulfate assimilation (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01540; -; 1.
PBIL [Tree]
InterPro IPR011786; CysI.
IPR006066; Nir_Si_BS.
IPR006067; Nir_Sir_4Fe4S.
IPR005117; NiRdtase/SiRdtase_haem-b_fer.
Graphical view of domain structure.
Pfam PF01077; NIR_SIR; 1.
PF03460; NIR_SIR_ferr; 2.
Pfam graphical view of domain structure.
PRINTS PR00397; SIROHAEM.
TIGRFAMs TIGR02041; CysI; 1.
PROSITE PS00365; NIR_SIR; 1.
BLOCKS Q66ED3.
Genome annotation databases
GeneID 2955406; -.
GenomeReviews BX936398_GR; YPTB0760.
KEGG yps:YPTB0760; -.
NMPDR fig|273123.1.peg.885; -.
Phylogenomic databases
HOGENOM Q66ED3; -.
Genome annotation databases
CMR Q66ED3; YPTB0760.
Other
ProtoNet Q66ED3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Amino-acid biosynthesis; Complete proteome; Cysteine biosynthesis; Heme; Iron; Iron-sulfur; Metal-binding; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   576  576     Sulfite reductase [NADPH] hemoprotein beta-component. PRO_0000199918
METAL   435   435        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   441   441        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   480   480        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   484   484        Iron (siroheme axial ligand) (By similarity). 
METAL   484   484        Iron-sulfur (4Fe-4S) (By similarity). 
Sequence information
Length: 576 AA [This is the length of the unprocessed precursor] Molecular weight: 64101 Da [This is the MW of the unprocessed precursor] CRC64: 976E5D7D48A69B43 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNEKHPGPLV VSGKLSDGER MKSESNFLRG TIAEDLNNGL TGGFSGDNFL LIRFHGMYQQ 

        70         80         90        100        110        120 
DDRDIRAERA EQKLEPRHAM MLRCRLPGGI ITPQQWLGID KFAADNTLYG SIRITNRQTF 

       130        140        150        160        170        180 
QFHGILKGNV KPAHQLLNEL GLDALATAND VNRNVLCTSN PVESALHQEA YEWAKKISEH 

       190        200        210        220        230        240 
LLPRTRAYAE IWLDAEKVAT TDEEPILGAT YLPRKFKTTV VIPPQNDVDL HANDLNFVAV 

       250        260        270        280        290        300 
ADKGKLIGFN VLVGGGLSIA HGDKNTYPRK ASEFGYIPLK HTLAIAEAVV TTQRDWGNRT 

       310        320        330        340        350        360 
DRKNAKTKYT LERVGVETFK AEVEKRAGVS FSAIKPYQFT GRGDRIGWVK GVDKKWHLTL 

       370        380        390        400        410        420 
FIENGRLLDY PGRSLKTGVA EIAKIHQGDF RLTANQNLIV AGVPEKDKAR IEALAREHGL 

       430        440        450        460        470        480 
MDDHVTSQRE NSMACVSFPT CPLAMAEAER FLPEFVTRVE GILQQHGLAD EHIVLRVTGC 

       490        500        510        520        530        540 
PNGCGRALLA EVGLVGKAVG RYNLHLGGNR EGTRIPRMYR ENITADEILL ITDQLVGRWA 

       550        560        570 
KERHVDEGFG DFVIRAGVIA PVIDSARDFY DVQEAM
Q66ED3 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ca flag CBR Canada Mirror sites: Australia Brazil China Korea Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!