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UniProtKB/Swiss-Prot entry Q6CIR6


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ETR1_KLULA
Primary accession number Q6CIR6
Secondary accession numbers None
Integrated into Swiss-Prot on April 26, 2005
Sequence was last modified on August 16, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 30)
Name and origin of the protein
Protein name Probable trans-2-enoyl-CoA reductase, mitochondrial [Precursor]
Synonym EC 1.3.1.38
Gene name
Name: ETR1
OrderedLocusNames: KLLA0F24552g
From
Kluyveromyces lactis (Yeast) (Candida sphaerica) [TaxID: 28985] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NRRL Y-1140 / WM37;
DOI=10.1038/nature02579; PubMed=15229592 [NCBI, ExPASy, EBI, Israel, Japan]
Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L.;
"Genome evolution in yeasts.";
Nature 430:35-44(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR382126; CAG98881.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_456173.1; -.
3D structure databases
ModBase Q6CIR6.
Ontologies
GO
GO:0019166; Molecular function: trans-2-enoyl-CoA reductase (NADPH) activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR013154; AlcDHase_GroES-like.
IPR002085; AlcDHase_SF_Zn.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR11695; ADH_Sf_Zn; 1.
Pfam PF08240; ADH_N; 1.
Pfam graphical view of domain structure.
BLOCKS Q6CIR6.
Genome annotation databases
GeneID 2895202; -.
KEGG kla:KLLA0F24552g; -.
Phylogenomic databases
HOGENOM Q6CIR6; -.
Other
ProtoNet Q6CIR6.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Fatty acid biosynthesis; Lipid synthesis; Mitochondrion; NADP; Oxidoreductase; Transit peptide.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
TRANSIT   1    17  17     Mitochondrion (Potential). 
CHAIN   18   382  365     Probable trans-2-enoyl-CoA reductase, mitochondrial. PRO_0000000902
Sequence information
Length: 382 AA [This is the length of the unprocessed precursor] Molecular weight: 42256 Da [This is the MW of the unprocessed precursor] CRC64: DE17CC6087A6A8FB [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSSFLSKRFL SFSQRAMSQE SLKFKSLIYS SHDSQDCTKV LKVHNYKPKK GSETSIVLKT 

        70         80         90        100        110        120 
LAFPINPSDI NQLEGVYPSK PDKVTDYSTD EPSAIAGNEG VFEVVSVPSS VSTLKPGDKV 

       130        140        150        160        170        180 
IPLQANFGTW STYRTCDKES DLIKIEGVDI YTAATVAVNG CTAYQLVNDY INWDPKGNDW 

       190        200        210        220        230        240 
LVQNAGTSSV SKIVTQIAKA KNINTLSVIR DRENFEEVAE ILEKKYGATK VISETENGEK 

       250        260        270        280        290        300 
EFGKEVLPKV LGSNAQVKLA LNSVGGKSCA NIARKLSKDG LMLTYGGMSK QPLTFPTGLF 

       310        320        330        340        350        360 
IFKGLKSHGF WVTENSKRDP ENKIKTVNEV IELYRDGKII SPKEDIRALE WDVNNASDEE 

       370        380 
VLQLITDGIK TKGTKNMVIL KW 

Q6CIR6 in FASTA format

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