ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q6G4F7

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name PYRD_BARHE
Primary accession number Q6G4F7
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on July 19, 2004 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 38)
Name and origin of the protein
Protein name Dihydroorotate dehydrogenase
Synonyms EC 1.3.3.1
Dihydroorotate oxidase
DHOdehase
DHODase
DHOD
Gene name
Name: pyrD
OrderedLocusNames: BH03870
From
Bartonella henselae (Rochalimaea henselae) [TaxID: 38323] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bartonellaceae; Bartonella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 49882 / Houston 1;
DOI=10.1073/pnas.0305659101; PubMed=15210978 [NCBI, ExPASy, EBI, Israel, Japan]
Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E.;
"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae.";
Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX897699; CAF27197.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_033228.1; -.
3D structure databases
ModBase Q6G4F7.
Enzyme and pathway databases
BioCyc BHEN283166:BH03870-MON; -.
Ontologies
GO
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from HAMAP).
GO:0004158; Molecular function: dihydroorotate oxidase activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00225; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR012135; DHO_DHase_1_2.
IPR005719; DHO_DHase_2.
IPR001295; Dihydroorotate_DHase_core.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF01180; DHO_dh; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000164; DHO_oxidase; 1.
TIGRFAMs TIGR01036; pyrD_sub2; 1.
PROSITE PS00911; DHODEHASE_1; 1.
PS00912; DHODEHASE_2; 1.
BLOCKS Q6G4F7.
Genome annotation databases
GeneID 2864782; -.
GenomeReviews BX897699_GR; BH03870.
KEGG bhe:BH03870; -.
NMPDR fig|283166.1.peg.356; -.
Phylogenomic databases
HOGENOM Q6G4F7; -.
Genome annotation databases
CMR Q6G4F7; BH03870.
Other
ProtoNet Q6G4F7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell membrane; Complete proteome; Flavoprotein; FMN; Membrane; Oxidoreductase; Pyrimidine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   362  362     Dihydroorotate dehydrogenase. PRO_0000336454
ACT_SITE   171   171        Nucleophile (By similarity). 
Sequence information
Length: 362 AA [This is the length of the unprocessed precursor] Molecular weight: 40555 Da [This is the MW of the unprocessed precursor] CRC64: 52B31703E536D0B4 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSFFRCIGRS ALFMLDPEHA HRLAIMGLKS GLNSYQKVVD NRLCVTIAGL KFENFIGLAA 

        70         80         90        100        110        120 
GFDKNAEVVN DVFHLGFGFT EIGTVTPRPQ VGNPKPRLFR LRKDEAIINR MGFNNDGRQI 

       130        140        150        160        170        180 
VYGRLHGYKR LGIVGINIGA NKDTVDKIDD YITSIAYFYD VADYFTVNIS SPNTPGLRDL 

       190        200        210        220        230        240 
QVRDSLHLLM NAISQARNEQ KKKHGFFVPI FLKIAPDLSE KELDDVAEEM KLSDFDGLIV 

       250        260        270        280        290        300 
SNTTLSRQGL RECTLRNEEG GLSGRPLFER STIVLAKMRQ KLGKKIAIIG VGGIRDAKTA 

       310        320        330        340        350        360 
LEKVKAGADL VQLYSGMVYE GPDLAITILK EILQFMQKDG VESIKAYRDQ RVEYWAKHML 


SS
Q6G4F7 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ca flag CBR Canada Mirror sites: Australia Brazil China Korea Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!