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UniProtKB/Swiss-Prot entry Q6L125

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G3P_PICTO
Primary accession number Q6L125
Secondary accession numbers None
Integrated into Swiss-Prot on August 30, 2005
Sequence was last modified on August 30, 2005 (Sequence version 2)
Annotations were last modified on    September 2, 2008 (Entry version 35)
Name and origin of the protein
Protein name Glyceraldehyde-3-phosphate dehydrogenase
Synonyms GAPDH
EC 1.2.1.59
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase
Gene name
Name: gap
OrderedLocusNames: PTO0742
From
Picrophilus torridus [TaxID: 82076] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Thermoplasmata; Thermoplasmatales; Picrophilaceae; Picrophilus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828;
DOI=10.1073/pnas.0401356101; PubMed=15184674 [NCBI, ExPASy, EBI, Israel, Japan]
Fuetterer O., Angelov A., Liesegang H., Gottschalk G., Schleper C., Schepers B., Dock C., Antranikian G., Liebl W.;
"Genome sequence of Picrophilus torridus and its implications for life around pH 0.";
Proc. Natl. Acad. Sci. U.S.A. 101:9091-9096(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE017261; AAT43327.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_023520.1; -.
3D structure databases
HSSP P39460; 1B7G. [HSSP ENTRY / PDB]
ModBase Q6L125.
Enzyme and pathway databases
BioCyc PTOR263820:PTO0742-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004365; Molecular function: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity (inferred from electronic annotation from HAMAP).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00559; -; 1.
PBIL [Tree]
InterPro IPR000173; GlycerAld_3-P_DHase.
IPR006436; Glyceraldehyde-3-P_DHase_2_arc.
Graphical view of domain structure.
PANTHER PTHR10836; GAP_DH; 1.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
ProDom PD007761; GAPDH_like; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01546; GAPDH-II_archae; 1.
PROSITE PS00071; GAPDH; 1.
BLOCKS Q6L125.
Genome annotation databases
GeneID 2845092; -.
GenomeReviews AE017261_GR; PTO0742.
KEGG pto:PTO0742; -.
NMPDR fig|263820.1.peg.742; -.
Phylogenomic databases
HOGENOM Q6L125; -.
Genome annotation databases
CMR Q6L125; PTO0742.
Other
ProtoNet Q6L125.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; NAD; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   341  341     Glyceraldehyde-3-phosphate dehydrogenase. PRO_0000145727
NP_BIND   11    12  2     NAD (By similarity). 
REGION   138   140  3     Glyceraldehyde 3-phosphate binding (By similarity). 
REGION   192   193  2     Glyceraldehyde 3-phosphate binding (By similarity). 
ACT_SITE   139   139        Nucleophile (By similarity). 
BINDING   109   109        NAD; via amide nitrogen (By similarity). 
BINDING   167   167        NAD (By similarity). 
BINDING   169   169        Glyceraldehyde 3-phosphate (By similarity). 
BINDING   299   299        NAD; via carbonyl oxygen (By similarity). 
Sequence information
Length: 341 AA [This is the length of the unprocessed precursor] Molecular weight: 38559 Da [This is the MW of the unprocessed precursor] CRC64: 388F45B97ECFDA93 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MIKVGINGYG TIGKRVAYAA SIQDDIHVSG IVKNTPDYMA YLASRSFNIY VPDDDKIKEF 

        70         80         90        100        110        120 
EDHGIKVKGT LNDLMESSDI IVDATPEGMG MENIKIYKKK RVKAIFQGGE KSNIGDASFN 

       130        140        150        160        170        180 
AYSNYNESFK REYTRVVSCN TTALARTLYP ILNDYGIENL NVTLIRRATD PNDNRKGPIN 

       190        200        210        220        230        240 
AIEPSMSFPS HHADDLKTVL NLNNVYTVAL KAPTTLMHVH SIEVLLKDDA KIDDIMESWL 

       250        260        270        280        290        300 
KYNRILLIEG KDNFKSTAQI MDMARELRRD RGDLYEIAIW RDSVKVIDKR LYYVQAVHQE 

       310        320        330        340 
SDVIPENIDA IRSLSGIDKN ESIEKTDKSL RISGGIFYGK E
Q6L125 in FASTA format

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