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UniProtKB/Swiss-Prot entry Q6LMN0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name E4PD_PHOPR
Primary accession number Q6LMN0
Secondary accession numbers None
Integrated into Swiss-Prot on July 10, 2007
Sequence was last modified on July 10, 2007 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 30)
Name and origin of the protein
Protein name D-erythrose-4-phosphate dehydrogenase
Synonyms E4PDH
EC 1.2.1.72
Gene name
Name: epd
OrderedLocusNames: PBPRA3132
From
Photobacterium profundum (Photobacterium sp. (strain SS9)) [TaxID: 74109] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Photobacterium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1103341; PubMed=15746425 [NCBI, ExPASy, EBI, Israel, Japan]
Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M., Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C., Bartlett D.H., Valle G.;
"Life at depth: Photobacterium profundum genome sequence and expression analysis.";
Science 307:1459-1461(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CR378673; CAG21447.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_131249.2; -.
3D structure databases
HSSP P06977; 1DC5. [HSSP ENTRY / PDB]
ModBase Q6LMN0.
Enzyme and pathway databases
BioCyc PPRO298386:PBPRA3132-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0048001; Molecular function: erythrose-4-phosphate dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0042823; Biological process: pyridoxal phosphate biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0008615; Biological process: pyridoxine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01640; -; 1.
PBIL [Tree]
InterPro IPR006422; E4P_DHase_bac.
IPR000173; GlycerAld_3-P_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 2.
PANTHER PTHR10836; GAP_DH; 1.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
PRINTS PR00078; G3PDHDRGNASE.
TIGRFAMs TIGR01532; E4PD_g-proteo; 1.
PROSITE PS00071; GAPDH; FALSE_NEG.
BLOCKS Q6LMN0.
Genome annotation databases
GeneID 3123661; -.
GenomeReviews CR354531_GR; PBPRA3132.
KEGG ppr:PBPRA3132; -.
NMPDR fig|298386.1.peg.5356; -.
Phylogenomic databases
HOGENOM Q6LMN0; -.
Genome annotation databases
CMR Q6LMN0; PBPRA3132.
Other
ProtoNet Q6LMN0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; NAD; Oxidoreductase; Pyridoxine biosynthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   360  360     D-erythrose-4-phosphate dehydrogenase. PRO_0000293152
NP_BIND   12    13  2     NAD (By similarity). 
REGION   159   161  3     Substrate binding (Potential). 
REGION   218   219  2     Substrate binding (Potential). 
ACT_SITE   160   160        Nucleophile (By similarity). 
BINDING   205   205        Substrate (Potential). 
BINDING   241   241        Substrate (Potential). 
BINDING   323   323        NAD (By similarity). 
SITE   187   187  1     Activates thiol group during catalysis (By similarity). 
Sequence information
Length: 360 AA [This is the length of the unprocessed precursor] Molecular weight: 39834 Da [This is the MW of the unprocessed precursor] CRC64: 71F1F3068FD89B04 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTLKVAINGF GRIGRSVLRA LYESGKHHHI NVVAVNELAE PEAMAHLLQY DSSHGRFFKP 

        70         80         90        100        110        120 
VSHDQEHLFI AHENGERDDI RILHQSDITL LPWHDLDVDI VLDCTGVYGS REDGLAHIKA 

       130        140        150        160        170        180 
GAKKVLFSHP AANDIDNTII YGVNHKTLTS EHRIVSNGSC TTNCIVPVIK IIDDAFGIES 

       190        200        210        220        230        240 
GTITTIHSAM NDQQVIDGYH SDLRRTRAAS QSIIPVDTKL HLGIGRIFPK FVDKFEAISV 

       250        260        270        280        290        300 
RVPTINVTAM DLSVTVKTNV KVNDVNQALS EVSRCTLEGI VDYTEAPLVS IDFNHDPHSA 

       310        320        330        340        350        360 
IVDGTQTRVS NKHLIKLLVW CDNEWGFANR MLDTALAMHA SDAAQHSNKE LRSKIAIKNS
Q6LMN0 in FASTA format

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