ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q6SZS5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name PYRD_CANGA
Primary accession number Q6SZS5
Secondary accession numbers None
Integrated into Swiss-Prot on August 31, 2004
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 37)
Name and origin of the protein
Protein name Dihydroorotate dehydrogenase, mitochondrial [Precursor]
Synonyms DHOdehase
DHODase
DHOD
EC 1.3.3.1
Dihydroorotate oxidase
Gene name
Name: URA9
OrderedLocusNames: CAGL0M12881g
From
Candida glabrata (Yeast) (Torulopsis glabrata) [TaxID: 5478] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; mitosporic Saccharomycetales; Candida.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 2001 / CBS 138 / IFO 0622 / NRRL Y-65;
Hall C.R., Dietrich F.S.;
Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 2001 / CBS 138 / IFO 0622 / NRRL Y-65;
DOI=10.1038/nature02579; PubMed=15229592 [NCBI, ExPASy, EBI, Israel, Japan]
Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L.;
"Genome evolution in yeasts.";
Nature 430:35-44(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AY444340; AAR17523.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
CR380959; CAG62883.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_449903.1; -.
3D structure databases
ModBase Q6SZS5.
Family and domain databases
InterPro IPR013785; Aldolase_TIM.
IPR012135; DHO_DHase_1_2.
IPR005719; DHO_DHase_2.
IPR001295; Dihydroorotate_DHase_core.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF01180; DHO_dh; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000164; DHO_oxidase; 1.
TIGRFAMs TIGR01036; pyrD_sub2; 1.
PROSITE PS00911; DHODEHASE_1; 1.
PS00912; DHODEHASE_2; 1.
BLOCKS Q6SZS5.
Genome annotation databases
GeneID 2891454; -.
KEGG cgr:CAGL0M12881g; -.
Phylogenomic databases
HOGENOM Q6SZS5; -.
Other
ProtoNet Q6SZS5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; FAD; Flavoprotein; Membrane; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; Pyrimidine biosynthesis; Transit peptide.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1     ?        Mitochondrion (Potential). 
CHAIN   ?   439        Dihydroorotate dehydrogenase, mitochondrial. PRO_0000029892
ACT_SITE   248   248        Nucleophile (By similarity). 
Sequence information
Length: 439 AA [This is the length of the unprocessed precursor] Molecular weight: 48217 Da [This is the MW of the unprocessed precursor] CRC64: E116514C9B8CCBB4 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MMHRVGFNVI GRRSFFTVNA RRQVLKSSFM GLKPLQLTAL LLAGSAGYLY FMNARSAIHE 

        70         80         90        100        110        120 
YVVCPVVRLI TPDPENGHKL GIWCFKWGLS PKLYFDKDPE SLHVNVFGTT MTNPIGCAAG 

       130        140        150        160        170        180 
LDKDAEAIDG IMPTGFGYME VGSVTPVAQP GNPRPRFFRL PADDAVINRY GFNSSGHDVV 

       190        200        210        220        230        240 
YNNLMKRVNK FLNSYFGDKS IDKLSLYKDK LLAVNLGKNK NGDEVKDYLK GVEKFQSLAD 

       250        260        270        280        290        300 
VLVINVSSPN TPGLRDLQNE AKLTNLLSEI ITKRDSQSNK PNALGKQNHK PPVLVKIAPD 

       310        320        330        340        350        360 
LTEPELQSIV EAAKKSKVDG IIVSNTTIQR PNTLKTQDET LRNQVGGLSG KPLKPFALKA 

       370        380        390        400        410        420 
MKAVSKYAKD SDLVLVGCGG ISSGKDAIEF AKAGATFVQL YTSYAYVGPA LIARIKDEVA 

       430 
EELKKEGKTW MEIIGEDNK 

Q6SZS5 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ca flag CBR Canada Mirror sites: Australia  Brazil  China  Korea  Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!