NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Venom gland;
DOI=10.1016/j.gene.2004.03.024; PubMed=15276202 [NCBI, ExPASy, EBI, Israel, Japan]
Francischetti I.M.B., My-Pham V., Harrison J., Garfield M.K., Ribeiro J.M.C.;
"Bitis gabonica (Gaboon viper) snake venom gland: toward a catalog for the full-length transcripts (cDNA) and proteins.";
Gene 337:55-69(2004).

Comments

FUNCTION: Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids. Inhibits platelet aggregation. Has an ability to induce apoptosis and hemorrhage. Has an antibacterial activity (By similarity).
CATALYTIC ACTIVITY: An L-amino acid + H₂O + O₂ = a 2-oxo acid + NH₃ + H₂O₂.
COFACTOR: FAD (By similarity).
SUBUNIT: Homodimer (By similarity).
SUBCELLULAR LOCATION: Secreted (By similarity).
TISSUE SPECIFICITY: Expressed by the venom gland.
PTM: Glycosylated (By similarity).
SIMILARITY: Belongs to the flavin monoamine oxidase family. FIG1 subfamily.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AY434453; AAR07363.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

SMR

Q6T627; 1-60.

ModBase

Q6T627.

Family and domain databases

BLOCKS

Q6T627.

Phylogenomic databases

HOVERGEN

Q6T627; -.

Other

ProtoNet

Q6T627.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Antibiotic; Antimicrobial; Apoptosis; Blood coagulation; FAD; Flavoprotein; Glycoprotein; Oxidoreductase; Secreted; Toxin.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`<1 >60`	`>60`	`L-amino-acid oxidase.`	`PRO_0000315371`
`NP_BIND`	`3 4`	`2`	`FAD (By similarity).`
`BINDING`	`4 4`		`Substrate (By similarity).`
`NON_TER`	`1 1`
`NON_TER`	`60 60`

Sequence information

Length: 60 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 7323 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: 584937BED0A03B07 [This is a checksum on the sequence]

        10         20         30         40         50         60 
GPMRIPEKHR IVREYIRKFG LQLNEFVQET ENAWYYIKNI RKKVHEVKKD PGLLKYPVKP

Q6T627 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools