[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. STRAIN=cv. Nipponbare; The international rice genome sequencing project (IRGSP) consortium; "Oryza sativa nipponbare chromosome 7 genomic DNA sequence."; Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
[2]	NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. STRAIN=cv. Nipponbare; DOI=10.1126/science.1081288; PubMed=12869764 [NCBI, ExPASy, EBI, Israel, Japan] The rice full-length cDNA consortium; "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."; Science 301:376-379(2003).

Comments

FUNCTION: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity).
CATALYTIC ACTIVITY: Succinate + ubiquinone = fumarate + ubiquinol.
COFACTOR: FAD (By similarity).
PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle .
SUBUNIT: Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit (By similarity).
SUBCELLULAR LOCATION: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side (By similarity).
SIMILARITY: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AP004338; BAC83515.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AK065901; -; NOT_ANNOTATED_CDS; mRNA.	[EMBL / GenBank / DDBJ]

RefSeq

NP_001058845.1; -.

UniGene

Os.22581

3D structure databases

HSSP

P00363; 1KF6. [HSSP ENTRY / PDB]

SMR

Q6ZDY8; 37-630.

ModBase

Q6ZDY8.

Organism-specific databases

Gramene

Q6ZDY8; -.

Family and domain databases

InterPro

IPR003953; FAD_bind2_N.
IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR003952; FRD_SDH_FAD_BS.
IPR004112; Fum_Rdtase/Succ_DHase_flav_C.
IPR011281; Succ_DHase_flav_su_fwd.
IPR014006; Succ_Dhase_frdA_Gneg.
Graphical view of domain structure.

Pfam

PF00890; FAD_binding_2; 1.
PF02910; Succ_DH_flav_C; 1.
Pfam graphical view of domain structure.

PRINTS

PR00368; FADPNR.

TIGRFAMs

TIGR01816; sdhA_forward; 1.
TIGR01812; sdhA_frdA_Gneg; 1.

PROSITE

PS00504; FRD_SDH_FAD_BINDING; 1.

BLOCKS

Q6ZDY8.

Genome annotation databases

GeneID

4342350; -.

KEGG

osa:4342350; -.

Other

ProtoNet

Q6ZDY8.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Electron transport; FAD; Flavoprotein; Membrane; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; Transit peptide; Transport; Tricarboxylic acid cycle.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`TRANSIT`	`1 31`	`31`	`Mitochondrion (Potential).`
`CHAIN`	`32 630`	`599`	`Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial.`	`PRO_0000247593`
`NP_BIND`	`75 90`	`16`	`FAD (By similarity).`
`ACT_SITE`	`325 325`		`Proton acceptor (By similarity).`
`BINDING`	`281 281`		`Substrate (By similarity).`
`BINDING`	`293 293`		`Substrate (By similarity).`
`BINDING`	`392 392`		`Substrate (By similarity).`
`BINDING`	`437 437`		`Substrate (By similarity).`
`MOD_RES`	`83 83`		`Tele-8alpha-FAD histidine (By similarity).`

Sequence information

Length: 630 AA [This is the length of the unprocessed precursor]

Molecular weight: 68854 Da [This is the MW of the unprocessed precursor]

CRC64: 9BDEE1ABC77CF08C [This is a checksum on the sequence]

        10         20         30         40         50         60 
MWRGCVSRGL RSLSKGKGSS SSAPVSAAAR LFSTASSSYT VVDHSYDAVV VGAGGAGLRA 

        70         80         90        100        110        120 
AIGLSEHGFN TACITKLFPT RSHTVAAQGG INAALGNMTE DDWRWHMYDT VKGSDWLGDQ 

       130        140        150        160        170        180 
DSIQYMCREA PKAVIELENY GLPFSRTEDG KIYQRAFGGQ SLDFGKGGQA YRCACAADRT 

       190        200        210        220        230        240 
GHAMLHTLYG QAMKHNTQFF VEYFALDLIM DSEGTCQGVI ALNMEDGTLH RFRATNTILA 

       250        260        270        280        290        300 
TGGYGRAYFS ATSAHTCTGD GNAMVARAGL PLQDLEFVQF HPTGIYGAGC LITEGSRGEG 

       310        320        330        340        350        360 
GILRNSEGER FMERYAPTAK DLASRDVVSR SMTMEIREGR GVGPLKDHIY LHLNHLPPEV 

       370        380        390        400        410        420 
LKERLPGISE TAAIFAGVDV TKEPIPVLPT VHYNMGGIPT NYHGEVVTMK GDNPDSVVPG 

       430        440        450        460        470        480 
LMAAGEAACA SVHGANRLGA NSLLDIVVFG RACANRVAET AKPGEKQKPL QKSAGEKTIA 

       490        500        510        520        530        540 
WLDKLRNANG SLPTSKIRLN MQRVMQNNAA VFRTQETLEE GCKLITKAWE SYHDVKISDR 

       550        560        570        580        590        600 
SLIWNSDLIE TIELENLLIN ACITMHSAEA RKESRGAHAR EDFTKRDDEQ WMKHSLGYWE 

       610        620        630 
NEKVRLAYRP VHMNTLDSEV ESFPPKARVY

Q6ZDY8 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools