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UniProtKB/Swiss-Prot entry Q72WY4


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GUAC_BACC1
Primary accession number Q72WY4
Secondary accession numbers None
Integrated into Swiss-Prot on July 19, 2004
Sequence was last modified on July 5, 2004 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 34)
Name and origin of the protein
Protein name GMP reductase
Synonyms EC 1.7.1.7
Guanosine 5'-monophosphate oxidoreductase
Guanosine monophosphate reductase
Gene name
Name: guaC
OrderedLocusNames: BCE_5594
From
Bacillus cereus (strain ATCC 10987) [TaxID: 222523] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1093/nar/gkh258; PubMed=14960714 [NCBI, ExPASy, EBI, Israel, Japan]
Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D.;
"The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1.";
Nucleic Acids Res. 32:977-988(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE017194; AAS44494.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_981886.1; -.
3D structure databases
SMR Q72WY4; 1-321.
ModBase Q72WY4.
Ontologies
GO
GO:0003920; Molecular function: GMP reductase activity (inferred from electronic annotation from HAMAP).
GO:0006163; Biological process: purine nucleotide metabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01511; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR005994; GMP_reduct2.
IPR015875; IMP_DH/GMP_Rdtase_CS.
IPR001093; IMP_DHase_GMPRtase.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF00478; IMPDH; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036500; GMP_red_Firmic; 1.
TIGRFAMs TIGR01306; GMP_reduct_2; 1.
PROSITE PS00487; IMP_DH_GMP_RED; 1.
BLOCKS Q72WY4.
Genome annotation databases
GeneID 2748968; -.
GenomeReviews AE017194_GR; BCE_5594.
KEGG bca:BCE_5594; -.
NMPDR fig|222523.1.peg.5558; -.
TIGR BCE_5594; -.
Phylogenomic databases
HOGENOM Q72WY4; -.
Other
ProtoNet Q72WY4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   327  327     GMP reductase. PRO_0000093747
NP_BIND   204   227  24     NADP (Potential). 
ACT_SITE   175   175        Thioimidate intermediate (By similarity). 
Sequence information
Length: 327 AA [This is the length of the unprocessed precursor] Molecular weight: 36113 Da [This is the MW of the unprocessed precursor] CRC64: 622222621599CB11 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MENVFDYEDI QLIPAKCIVN SRSECDTTVT LGKHKFKLPV VPANMQTIID ERIATYLAEN 

        70         80         90        100        110        120 
NYFYIMHRFQ PEKRISFIRD MQSRGLIASI SVGVKADEYE FVQQLAAEHL TPEYITIDIA 

       130        140        150        160        170        180 
HGHSNAVINM IQHIKKHLPE SFVIAGNVGT PEAVRELENA GADATKVGIG PGKVCITKIK 

       190        200        210        220        230        240 
TGFGTGGWQL AALRWCAKAA SKPIIADGGI RTHGDVAKSI RFGATMVMIG SLFAGHEESP 

       250        260        270        280        290        300 
GETIEKDGKL YKEYFGSASE FQKGEKKNVE GKKMFVEHKG SLEDTLIEME QDLQSSISYA 

       310        320 
GGTKLDSIRT VDYVVVKNSI FNGDKVY 

Q72WY4 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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